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. 2025 Apr 25;12:1500901. doi: 10.3389/fmed.2025.1500901

Table 4.

Bi-variable logistic regression analysis to identify factors of VAP among adult intensive care unit admitted patients in public hospitals in Addis Ababa, Ethiopia, 2024.

Variable Category Ventilator-Associated Pneumonia (VAP)
Yes No COR 95%CI P-value
Age <60 65 (61.9%) 206 (89.6%) 1 1
> = 60 40 (38.1%) 24 (10.4%) 5.282 2.964–9.413 0.000
Sex Male 68 (64.8%) 123 (53.4%) 1.599 0.992–2.576 0.054
Female 37 (35.2%) 107 (46.6%)
Re-intubation Yes 73 (69.5%) 40 (17.4%) 10.836 6.330–18.548 0.000
No 32 (30.5%) 190 (82.6%)
H2 blocker Yes 57 (54.3%) 150 (65.2%) 0.633 0.396–1.013 0.057
No 48 (45.7%) 80 (34.8%)
Corticosteroid use Yes 77 (73.3%) 178 (77.4%) 0.803 0.472–1.367 0.419
No 28 (26.7%) 52 (22.6%)
Tracheostomy Yes 63 (60%) 35 (15.2%) 8.357 4.914–14.212 0.000
No 42 (40%) 195 (84.8%)
Day on MV >14 90 (85.7%) 82 (35.7%) 10.829 5.887–19.922 0.000
<=14 15 (14.3%) 148 (64.3%)
Emergency intubation Yes 57 (54.3%) 70 (30.4%) 2.714 1.687–4.368 0.000
No 48 (45.7%) 160 (69.6%)
Taken ≥3 antibiotics Yes 39 (37.1%) 83 (36%) 1.047 0.648–1.689 0.852
No 66 (62.9%) 147 (64%)
Blood transfusion Yes 41 (39%) 91 (39.6%) 0.979 0.610–1.570 0.928
No 64 (61%) 139 (60.4%)
Supine head position Yes 17 (16.2%) 45 (19.6%) 0.794 0.430–1.466 0.461
No 88 (83.8%) 185 (80.4%)
Comorbidity Yes 43 (41%) 82 (35.7%) 1.252 0.780–2.010 0.353
No 62 (59%) 148 (64.3%)
Pulmonary Yes 49 (46.7%) 88 (38.3%) 1.412 0.885–2.251 0.147
No 56 (53.3%) 142 (61.7%)
Low GCS Yes 52 (49.5%) 95 (41.3%) 1.394 0.877–2.217 0.160
No 53 (50.5%) 135 (58.7%)
Head trauma Yes 48 (45.7%) 87 (37.8%) 1.384 0.867–2.209 0.173
No 57 (54.3%) 143 (62.2%)
Burn Yes 4 (3.8%) 23 (10%) 0.356 0.120–1.058 0.063
No 101 (96.2%) 207 (90%)
Cardiac Yes 8 (7.6%) 39 (17%) 0.404 0.182–0.898 0.026
No 97 (92.4%) 191 (83%)

*PV < 0.05 statistically significant, 1 = reference.

AOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio; MV, mechanical Ventilator; GCS, Glasgow Coma Scale.