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. 2025 Apr 25;12:1500901. doi: 10.3389/fmed.2025.1500901

Table 5.

Multivariable analysis to identify factors of VAP among adult intensive care unit admitted patients in public hospitals in Addis Ababa, Ethiopia, 2024.

Variable Category Ventilator-Associated Pneumonia (VAP)
Yes No COR 95%CI P-value AOR 95%CI P-value
Age <60 65 (61.9%) 206 (89.6%) 1 1
≥60 40 (38.1%) 24 (10.4%) 5.282 2.964–9.413 0.000 3.293 1.521–7.127 0.002 *
Sex Male 68 (64.8%) 123 (53.4%) 1.599 0.992–2.576 0.054 0.946 0.496–1.802 0.865
Female 37 (35.2%) 107 (46.6%) 1
Re-intubation Yes 73 (69.5%) 40 (17.4%) 10.836 6.330–18.548 0.000 4.808 2.439–9.478 0.000 *
No 32 (30.5%) 190 (82.6%) 1
H2 blocker Yes 57 (54.3%) 150 (65.2%) 0.633 0.396–1.013 0.057 0.653 0.338–1.263 0.205
No 48 (45.7%) 80 (34.8%) 1
Tracheostomy Yes 63 (60%) 35 (15.2%) 8.357 4.914–14.212 0.000 2.510 1.208–5.213 0.014 *
No 42 (40%) 195 (84.8%) 1
Day on MV >14 90 (85.7%) 82 (35.7%) 10.829 5.887–19.922 0.000 3.242 1.445–7.276 0.004 *
<=14 15 (14.3%) 148 (64.3%) 1
Emergency intubation Yes 57 (54.3%) 70 (30.4%) 2.714 1.687–4.368 0.000 2.452 1.305–4.606 0.005 *
No 48 (45.7%) 160 (69.6%) 1
Pulmonary Yes 49 (46.7%) 88 (38.3%) 1.412 0.885–2.251 0.147 2.067 0.567–7.537 0.271
No 56 (53.3%) 142 (61.7%) 1
Low GCS Yes 52 (49.5%) 95 (41.3%) 1.394 0.877–2.217 0.160 0.963 0.467–1.984 0.918
No 53 (50.5%) 135 (58.7%) 1
Head trauma Yes 48 (45.7%) 87 (37.8%) 1.384 0.867–2.209 0.173 3.968 0.934–16.860 0.062
No 57 (54.3%) 143 (62.2%) 1
Burn Yes 4 (3.8%) 23 (10%) 0.356 0.120–1.058 0.063 0.913 0.146–5.713 0.922
No 101 (96.2%) 207 (90%) 1
Cardiac Yes 8 (7.6%) 39 (17%) 0.404 0.182–0.898 0.026 0.766 0.184–3.194 0.715
No 97 (92.4%) 191 (83%) 1

*Indicates statistically significant, 1 = reference.

AOR, adjusted odds ratio; CI, confidence interval; COR, crude odds ratio; MV, mechanical Ventilator; GCS, Glasgow Coma Scale.