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. 2025 Apr 25;16:1503449. doi: 10.3389/fphar.2025.1503449

TABLE 2.

Trends in hepatic and renal function and coagulation indices in patients undergoing treatment.

Coagulation function 1 h post- poisoning 12 h post- poisoning (Day 1) 36 h post- poisoning (Day 2) 60 h post- poisoning (Day 3) Reference value range
ALT (U/L) 11.2 106.7 64.2 20.2 0–50
AST (U/L) 20.5 92 31.5 14.9 0–40
γ-GT (U/L) 12.2 19.1 12.1 18.4 0–60
ALP (g/L) 105.6 109.2 85.2 75 40–150
TP (umol/L) 80.27 77.14 55.64 56.34 40–55
TBil (umol/L) 8.79 19.78 9.65 6.42 2.0–20.4
CBil (umol/L) 1.23 6.8 0–6.8
Urea (mmol/L) 4.96 2.75 1.07 2.66 1.7–8.3
Cr (umol/L) 42.49 26 43.6 36.3 44–120
UA (umol/L) 252.6 208–428
PTA 87 55 59
PT(s) 11.9 17 16 11–14
INR 1.11 1.6 1.5 0.8–1.2
APTT(s) 28.8 34.8 36.5 20–40
Fig (g/L) 4.13 3.58 4.52 2–4
TT(s) 14.3 14.4 14 16–18
UA (umol/L) 252.6 208–428

ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-Gamma Glutamyl Transpeptidase; ALP, alkaline phosphatase; TP, total protein; Tbil, Total Bilirubin; Cbil, Conjugated Bilirubin; Cr, Creatinine; UA, uric acid; PTA, prothrombin activity; PT, prothrombin time; INR, international normalized ratio; APTT, Activated Partial Thrombo-plastin Time; Fig, Fibrinogen; TT, thrombin time.