TABLE 4.

Plasma pharmacokinetic parameters of puerarin after oral administration of CR-PLR granules and PLR granules in the normal group of rats (‾x ± SD, n = 6).

Parameters	CR-PLR	PLR
Cmax (μg/L)	6,002.78 ± 2,285.85	4,241.59 ± 1,084.43
Tmax (min)	16.00 ± 4.90	12.00 ± 4.00
t1/2 (min)	394.06 ± 40.01	217.42 ± 44.69*
AUC0-12 (μg/L·min)	1,275,552.32 ± 141,773.27	801,072.80 ± 60,592.92*
AUC0-∞ (μg/L·min)	1,724,483.50 ± 206,055.43	891,503.08 ± 44,305.01*
MRT0-t (min)	256.99 ± 31.68	233.36 ± 9.40

*P < 0.05, Indicates significant difference (CR-PLR group compared with PLR group).