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. 2025 Apr 25;16:1560271. doi: 10.3389/fphar.2025.1560271

TABLE 5.

Plasma pharmacokinetic parameters of cinnamic acid after oral administration of CR-PLR granules and CR granules in the model group of rats (‾x ± SD, n = 6).

Parameters CR-PLR CR
Cmax (μg/L) 723.28 ± 115.24 533.42 ± 70.01
Tmax (min) 10.00 15.00 ± 5.00
t1/2 (min) 329.42 ± 48.07 365.65 ± 92.99
AUC0-12 (μg/L·min) 232,832.48 ± 47,399.51 143,032.11 ± 10,673.33
AUC0-∞ (μg/L·min) 292,142.24 ± 44,006.00 188,352.51 ± 6,196.84
MRT0-t (min) 271.13 ± 7.89 276.78 ± 19.00