TABLE 6.

Plasma pharmacokinetic parameters of puerarin after oral administration of CR-PLR granules and PLR granules in the model group of rats (‾x ± SD, n = 6).

Parameters	CR-PLR	PLR
Cmax (μg/L)	2,756.55 ± 951.48	1,578.23 ± 252.05
Tmax (min)	15.00 ± 5.00	15.00 ± 5.00
t1/2 (min)	990.94 ± 154.60	469.65 ± 111.16*
AUC0-12 (μg/L·min)	429,132.95 ± 116,848.53	381,001.35 ± 3,482.60
AUC0-∞ (μg/L·min)	951,618.25 ± 162,505.14	558,079.40 ± 5,039.27*
MRT0-t (min)	278.97 ± 4.33	292.93 ± 9.58

*P < 0.05, Indicates significant difference (CR-PLR group compared with PLR group).