Table 2.

Association of COPD/SAR with all-cause and respiratory mortality using the FNIH criteria

Character	Crude model		Model 1		Model 2		Model 3
	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P
All-cause mortality
COPD-/SAR-	1 (ref)		1 (ref)		1 (ref)		1 (ref)
COPD-/SAR+	3.48(3.12, 3.89)	< 0.0001	1.39(1.25, 1.55)	< 0.0001	1.34(1.21, 1.48)	< 0.0001	1.33(1.20, 1.48)	< 0.0001
COPD+/SAR-	4.47(3.57, 5.60)	< 0.0001	2.27(1.81, 2.84)	< 0.0001	1.94(1.57, 2.38)	< 0.0001	1.51(1.21, 1.88)	< 0.001
COPD+/SAR+	9.28(6.33, 13.60)	< 0.0001	2.62(1.92, 3.57)	< 0.0001	2.24(1.64, 3.07)	< 0.0001	1.87(1.32, 2.66)	< 0.001
p for trend		< 0.0001		< 0.0001		< 0.0001		< 0.0001
Respiratory mortality
COPD-/SAR-	1 (ref)		1 (ref)		1 (ref)		1 (ref)
COPD-/SAR+	4.38(2.76, 6.95)	< 0.0001	1.39(0.86, 2.27)	0.18	1.26(0.74, 2.13)	0.39	1.82(0.91, 3.63)	0.09
COPD+/SAR-	33.61(21.68, 52.12)	< 0.0001	12.12(7.25, 20.25)	< 0.0001	9.54(5.66,16.08)	< 0.0001	5.16(2.96, 9.01)	< 0.0001
COPD+/SAR+	74.51(38.40, 144.57)	< 0.0001	12.37(6.36, 24.06)	< 0.0001	10.95(5.38,22.28)	< 0.0001	8.69(3.95, 19.14)	< 0.0001
p for trend		< 0.0001		< 0.0001		< 0.0001		< 0.0001

Abbreviations: HR, hazard ratio; CI, confidence interval

Crude model

Model 1: Age, sex

Model 2: Age, sex, ethnicity, marital, family income, educational level

Model 3: Age, sex, ethnicity, marital, family income, educational level, BMI, waist circumference, hemoglobin, TG, total cholesterol, HDL, Total bilirubin, HbA1c, smoke, UACR, eGFR, alcohol use