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. 2025 May 10;25:236. doi: 10.1186/s12871-025-03074-2

Table 1.

Patient antiemetic use characteristics

Variable Total Antiemetic use P-value
No Yes
Patient number (N) 967 867 (89.7%) 100 (10.3%)
Baseline characteristics
Age 53.70 ± 15.57 54.49 ± 15.27 46.87 ± 16.55 < 0.001
Gender 0.002
 Male 307 (31.7%) 289 (33.3%) 18 (18.0%)
 Female 660 (68.3%) 578 (66.7%) 82 (82.0%)
Kidney function
eGFR 84.62 ± 32.22 83.61 ± 28.48 93.38 ± 54.27 0.079
Body measurement
 Waist/Hip 0.91 ± 0.08 0.91 ± 0.08 0.90 ± 0.07 0.460
 BMI 26.57 ± 6.59 26.08 ± 6.16 30.81 ± 8.42 < 0.001
Other data
 Diabetes 198 (20.5%) 173 (20.0%) 25 (25.0%) 0.236
 Smoking 230 (23.8%) 221 (25.5%) 9 (9.0%) < 0.001
 Anesthesia time 186.71 ± 90.89 187.87 ± 92.51 176.61 ± 75.07 0.241
Surgery method < 0.001
 Upper abdominal 129 (13.3%) 125 (14.4%) 4 (4.0%)
 Lower abdominal 89 (9.2%) 85 (9.8%) 4 (4.0%)
 Laparoscopic surgery 210 (21.7%) 157 (18.1%) 53 (53.0%)
 VAT 148 (15.3%) 130 (15.0%) 18 (18.0%)
 Other a 391 (40.4%) 370 (42.7%) 21 (21.0%)
Pain
 NRS rest 2.33 ± 1.39 2.32 ± 1.40 2.41 ± 1.27 0.573
 NRS move 4.62 ± 1.73 4.64 ± 1.75 4.51 ± 1.51 0.465
 NRS cough 5.48 ± 1.82 5.51 ± 1.85 5.24 ± 1.52 0.096
Outcome information
 Bad sleep 532 (55.0%) 459 (52.9%) 73 (73.0%) < 0.001
 Bad vitality 172 (17.8%) 141 (16.3%) 31 (31.0%) < 0.001
 Bad sleep and vitality 132 (13.7%) 104 (12.0%) 28 (28.0%) < 0.001
PONV Score
 RINVR 4.83 ± 7.57 3.34 ± 6.04 17.72 ± 7.26 < 0.001
 SPONVSS 1.82 ± 3.02 1.22 ± 2.37 6.98 ± 3.15 < 0.001

a Other methods include thyroid cancer surgery, breast surgery, orthopedic surgery, and spine surgery

eGFR: estimated Glomerular filtration rate, VAT: Video-assisted thoracotomy, NRS: Numerical rating scale, BMI: body mass index, eGFR: estimated glomerular filtration rate, SPONVSS: simplified postoperative nausea and vomiting severity score (0–12)