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. 2025 Apr 28;16:1573986. doi: 10.3389/fendo.2025.1573986

Table 1.

Baseline characteristics of patients grouped by median TyG index.

Variables TyG index P value
Overall, N = 186 Low, N = 93 High, N = 93
Sex 0.377
 Female 84 (45.2%) 45 (48.4%) 39 (41.9%)
 Male 102 (54.8%) 48 (51.6%) 54 (58.1%)
Age (years) 0.141
 ≤60 100 (53.8%) 55 (59.1%) 45 (48.4%)
 >60 86 (46.2%) 38 (40.9%) 48 (51.6%)
BMI 22.8 (21.1, 24.4) 22.8 (20.7, 23.2) 22.9 (21.5, 25.3) 0.015
NEUT (*109/L) 3.86 (3.07, 4.97) 3.69 (2.87, 4.75) 3.88 (3.15, 4.99) 0.236
LYM (*109/L) 1.20 (0.84, 1.69) 1.13 (0.79, 1.54) 1.27 (0.99, 1.79) 0.078
HB (g/L) 124 (109, 137) 121 (102, 136) 126 (112, 140) 0.080
PLT (*109/L) 210 (168, 279) 210 (170, 290) 209 (167, 263) 0.482
ALB (g/L) 39.3 (38.3, 42.2) 39.3 (38.2, 40.9) 39.7 (38.5, 42.7) 0.056
FBG (mmol/L) 5.45 (4.79, 6.69) 5.15 (4.65, 5.61) 6.36 (5.24, 7.98) <0.001
TG (mmol/L) 1.34 (0.96, 1.88) 1.00 (0.80, 1.22) 1.87 (1.48, 2.44) <0.001
TC (mmol/L) 4.18 (3.58, 4.73) 4.13 (3.55, 4.61) 4.22 (3.66, 5.01) 0.126
HDL (mmol/L) 1.01 (0.82, 1.29) 1.05 (0.82, 1.36) 0.99 (0.82, 1.19) 0.069
LDL (mmol/L) 2.46 (2.07, 2.91) 2.45 (2.13, 2.88) 2.46 (2.04, 2.91) 0.880
ApoA (g/L) 1.09 (0.85, 1.40) 1.03 (0.78, 1.37) 1.14 (0.91, 1.40) 0.167
ApoB (g/L) 0.85 (0.70, 0.95) 0.82 (0.67, 0.91) 0.85 (0.76, 0.98) 0.009
LDH 0.761
 Low 118 (63.4%) 60 (64.5%) 58 (62.4%)
 High 68 (36.6%) 33 (35.5%) 35 (37.6%)
ECOG PS 0.203
 Low 169 (90.9%) 87 (93.5%) 82 (88.2%)
 High 17 (9.1%) 6 (6.5%) 11 (11.8%)
B symptoms 0.084
 No 153 (82.3%) 81 (87.1%) 72 (77.4%)
 Yes 33 (17.7%) 12 (12.9%) 21 (22.6%)
Hans 0.091
 Non-GCB 121 (65.1%) 66 (71.0%) 55 (59.1%)
 GCB 65 (34.9%) 27 (29.0%) 38 (40.9%)
Extranodal site 0.426
 0 129 (69.4%) 67 (72.0%) 62 (66.7%)
 1 57 (30.6%) 26 (28.0%) 31 (33.3%)
Ann Arbor stage 0.657
 Low 81 (43.5%) 42 (45.2%) 39 (41.9%)
 High 105 (56.5%) 51 (54.8%) 54 (58.1%)
IPI 0.875
 0-2 127 (68.3%) 64 (68.8%) 63 (67.7%)
 3-5 59 (31.7%) 29 (31.2%) 30 (32.3%)
Ki 67 0.73 (0.70, 0.80) 0.73 (0.70, 0.80) 0.80 (0.70, 0.80) 0.633
NLR 3.1 (2.0, 5.0) 3.1 (2.0, 5.0) 3.3 (2.0, 4.8) 0.862
PLR 182 (117, 280) 192 (117, 317) 175 (116, 247) 0.062
SII 654 (384, 1,280) 687 (360, 1,360) 645 (392, 1,164) 0.754

BMI, body mass index; NEUT, neutrophil count; LYM, lymphocyte count; HB, hemoglobin; PLT, platelet count; ALB, albumin; ECOG PS, eastern cooperative oncology group performance status; GCB, germinal center B-cell; IPI, international prognostic index; LDH, lactate dehydrogenase; FBG, fasting blood glucose; TG, triacylglycerol; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA, apolipoprotein A; ApoB, apolipoprotein B; TyG index, triglyceride glucose index; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; SII, systemic immune inflammation index.