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. 2025 Apr 28;16:1526518. doi: 10.3389/fimmu.2025.1526518

Table 3.

Head and neck.

Publication Year Purpose Image Modality Patients Ground Truth Key Innovation Outcome
Groendahl et al. (55) 2021 Tumors and involved nodes segmentation PET/CT 197 Manual GTV delineation Comparison of Traditional Methods with Machine Learning and Deep Learning Approaches Dice = 0.75
Taku et al. (56) 2022 Involved LN segmentation CT 110 Pathological Report Use DL-CNN to segment GTVT for HPV-associated OPC Dice = 0.92
Tekchandani et al. (57) 2022 LN segmentation and metastatic
analysis
CT 175 Pathological Report Introduced LNdtnNet: combines attention, residual UNet, squeeze-excitation for CT Dice = 0.94
Wu et al. (58) 2022 Metastatic LN detection CT 114 Pathologically Confirmed Integrated lymph node features with GCN for top performance. mFROC = 0.63
Bollen et al. (59) 2023 GTV segmentation CT/PET/MRI 170 GTV delineation Developed automated GTV delineation using 3D CNN with multimodal imaging mDice = 0.89
Ariji et al. (60) 2022 Metastatic cervical LN segmentation CT 158 Histopathological diagnosis Utilize the U-Net architecture to segment metastatic cervical lymph nodes F1 = 0.83
Liao et al. (61) 2025 Involved LN segmentation CT 626 Manual segmentation Used a two-stage transfer learning approach with nnUNet pretraining Dice = 0.72
Al Hasan et al. (62) 2024 Small normal lymph nodes segmentation CT 221 Manual segmentation Enhanced Attentional U- Net by filtering encoder features for segmentation Dice = 0.81