Table 4.
Biochemical characteristics of the study and control group.
| Parameter | Cyanotic patients (n = 36) | Control group (n = 30) | Cyanotic patients vs. control group (p-value) |
|---|---|---|---|
| Baseline characteristics | |||
| Hematocrit (%) | 0.5 (0.35–0.73) | 0.41 (0.33–0.47) | <0 . 001 |
| Hemoglobin (mmol/L) | 11.1 (±2.1) | 8.7 (±0.8) | <0 . 001 |
| Red blood cells (1012/L) | 5.85 (±1.3) | 4.5 (±1.1) | <0 . 001 |
| Platelets (109/L) | 151.5 (57–339) | 212 (171–319) | <0 . 001 |
| White blood cells (109/L) | 5.5 (2.8–9.9) | 6.1 (4–9.9) | 0.7 |
| Total cholesterol (mmol/L) | 4.1(±0.9) | 4.75 (±0.5) | 0 . 003 |
| LDL cholesterol (mmol/L) | 2.6 (±0.9) | 3.0 (±0.8) | 0.08 |
| HDL cholesterol (mmol/L) | 1.3 (±0.3) | 1.6 (±0.4) | 0 . 02 |
| Triglicerydes (mmol/L) | 1.1 (0.5–2.3) | 1.1 (0.6–2.2) | 0.5 |
| Creatinine (umol/L) | 75.5 (48–396) | 77.5 (57–107) | 0.9 |
| hsCRP (mg/L) | 2 (2–20) | 2 (2–26) | 0.07 |
| Fibrinogen (mg/dl) | 275.2 (±69.2) | 270.2 (±46.5) | 0.7 |
| ApoM (ng/ml) | 278.5 (260.4–308) | 301.9 (290.3–308.6) | 0 . 04 |
| S1P (pg/ml) | 213.9 (107.3–2,832.4) | 179 (95.5–300.8) | 0 . 04 |
| Albumin (g/L) | 40.5 (27–48) | 41 (36–49) | 0.7 |
| Total bilirubin (umol/L) | 21.5 (7.4–83.3) | 14.5 (4.1–25.3) | p < 0.001 |
| Unconjugated bilirubin (umol/L) | 14.7 (4.1–60.1) | 10.8 (2.1–18.3) | p < 0.001 |
| Unconjugated bilirubin (umol/L) | 7 (2.3–58.1) | 4.4 (2.3–9) | p < 0.001 |
APTT, activate partial thromboplastin time; ApoM, apolipoprotein M; INR, international normalized ratio; HDL, high density lipoprotein; hsCRP, hidgh sensitivity C-reactive protein; LDL, low density lipoprotein; NTproBNP, N-terminal prohormone of brain natriuretic peptide; PT, prothrombin time; S1P, sfingozyno-1-phosphorus.
Bold values are statistically significant.