Table 3. In Vitro Off-Target Profiles of Lead Compounds.
| compound | 
Ki ± 95% CI | 
|||||
|---|---|---|---|---|---|---|
| May1 (pM) | HIV-1 Pr (μM) | pepsin (μM) | renin (μM) | cathepsin D (nM) | cathepsin E (nM) | |
| 9 | 400 ± 200 | >500 | 7.6 ± 2.5 | >100 | 64 ± 8 | 26 ± 2 | 
| 25 | 180 ± 150 | >500 | 1.9 ± 0.9 | >500 | 37 ± 3 | 91 ± 10 |