Table 3. Summary of In Vitro Assaysa.
| ID# | stability in SGF and SIFb | cell viability relative IC50 (μM)b | hERG assay IC50 (μM)b | protein binding in mouse brainb | mini-Ames assayb |
|---|---|---|---|---|---|
| BNS807 | ND | 17.95 | 18.04 | ND | ND |
| BNS808 | stable | 16.84 | 5.39 | high | nonmutagenicb |
| BNS815 | ND | 46.69 | 4.86 | ND | ND |
| BNS825 | ND | >100 | ND | ND | ND |
ND = not determined.
Detailed Results in the Supplementary Tables 3–9.