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. 2025 Apr 21;68(9):9431–9445. doi: 10.1021/acs.jmedchem.4c03132

Table 3. Summary of In Vitro Assaysa.

ID# stability in SGF and SIFb cell viability relative IC50 (μM)b hERG assay IC50 (μM)b protein binding in mouse brainb mini-Ames assayb
BNS807 ND 17.95 18.04 ND ND
BNS808 stable 16.84 5.39 high nonmutagenicb
BNS815 ND 46.69 4.86 ND ND
BNS825 ND >100 ND ND ND
a

ND = not determined.

b

Detailed Results in the Supplementary Tables 3–9.