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. 2025 Apr 28;16:1557717. doi: 10.3389/fphar.2025.1557717

TABLE 5.

The results of the enrichment of the GO Biological Processes of each module.

MCODE GO Description Log10 (P)
My List GO:0010562 Positive regulation of phosphorus metabolic process −60.0
GO:0045937 Positive regulation of phosphate metabolic process −60.0
GO:0042327 Positive regulation of phosphorylation −57.3
MCODE 1 GO:0045834 Positive regulation of lipid metabolic process −10.9
GO:0030335 Positive regulation of cell migration −9.7
GO:2000147 Positive regulation of cell motility −9.6
MCODE 2 GO:0007169 Transmembrane receptor protein tyrosine kinase signalling pathway −37.4
GO:0007167 Enzyme-linked receptor protein signalling pathway −34.0
GO:0042327 Positive regulation of phosphorylation −30.4
MCODE 3 GO:0007169 Transmembrane receptor protein tyrosine kinase signalling pathway −21.6
GO:0042327 Positive regulation of phosphorylation −20.9
GO:0010562 Positive regulation of phosphorus metabolic process −20.2
MCODE 4 GO:0009725 Response to hormone −11.4
GO:0030335 Positive regulation of cell migration −10.7
GO:2000147 Positive regulation of cell motility −9.5
MCODE 5 GO:0045786 Negative regulation of cell cycle −9.5
GO:0007346 Regulation of mitotic cell cycle −8.7
GO:0045930 Negative regulation of mitotic cell cycle −8.5
MCODE 6 GO:0098703 Calcium ion import across plasma membrane −17.6
GO:0097553 Calcium ion transmembrane import into cytosol −14.7
GO:0098659 Inorganic cation import across plasma membrane −14.6
MCODE 7 GO:0007204 Positive regulation of cytosolic calcium ion concentration −9.0
GO:0006954 Inflammatory response −7.0
GO:0019932 Second-messenger-mediated signalling −5.8
MCODE 8 GO:0044597 Daunorubicin metabolic process −14.4
GO:0044598 Doxorubicin metabolic process −14.2
GO:0030638 Polyketide metabolic process −14.2
MCODE 9 GO:0120178 Steroid hormone biosynthetic process −9.1
GO:0042446 Hormone biosynthetic process −8.6
GO:0006694 Steroid biosynthetic process −7.3