Table III.

MRI volumetric signal intensity values and severity classes of clinical impairment.

Signal asymmetry ratio Median [IQR]	Audiological severity class 0	Audiological severity class 1		Audiological severity class 2	p value (classes 0-1)	p value (classes 1-2)	p value (classes 0-2)
nT2Max (cochlea)	1.03 [IQR 0.95-1.05]	1.02 [IQR 0.93-1.11]		0.85 [IQR 0.75-0.95]	0.96	0.009	0.011
nT2mean (cochlea)	0.99 [IQR 0.94-1.09]	0.96 [IQR 0.93-1.004]		0.74 [IQR 0.41-0.85]	0.71	0.001	0.003
Signal asymmetry ratio Median [IQR]	Audio-vestibular severity class 1		Audio-vestibular severity class 2		p value (classes 1-2)
nT2Max (inner ear)	0.98 [IQR 0.97–1.04]		0.82 [IQR 0.72.–0.93]		< 0.001
nT2mean (inner ear)	0.99 [IQR 0.96–1.07]		0.79 [IQR 0.43.–0.86]		<0.001
nT2Max: normalised maximum signal intensity value on T2-weighted images; nT2mean: normalised mean signal intensity value on T2-weighted images.
Only significant values of quantitative measures shown in Tab. III were used to differentiate clinical severity classes.