Table 3.
Potential candidate targets of Prunella vulgaris L. for treating non-small cell lung cancer
| No | Gene symbol | P value | logFC | No | Gene symbol | P value | log FC |
|---|---|---|---|---|---|---|---|
| 1 | AKR1B10 | 0.0000866 | 2.3932595 | 21 | ACHE | 0.0415 | 3.5809483 |
| 2 | ADORA3 | 0.000332 | 1.5149787 | 22 | NOS2 | 0.00000115 | −2.9362951 |
| 3 | SERPINA6 | 0.000388 | 1.6530115 | 23 | PDE4D | 0.00000708 | −1.8826387 |
| 4 | GCGR | 0.000427 | 1.079908 | 24 | CA4 | 0.0000316 | −4.677416 |
| 5 | CYP1B1 | 0.00129 | 2.353458 | 25 | CHRM2 | 0.000517 | −1.0184839 |
| 6 | MMP12 | 0.00129 | 4.3452597 | 26 | ABCB1 | 0.000757 | −3.130854 |
| 7 | CAMK2B | 0.00175 | 1.5617937 | 27 | CDK6 | 0.00093 | −1.4464042 |
| 8 | HSD17B2 | 0.00207 | 1.3030574 | 28 | ABCG2 | 0.00117 | −1.2862328 |
| 9 | NEK6 | 0.00293 | 1.1406784 | 29 | AKR1C1 | 0.00167 | −1.6951737 |
| 10 | TOP2A | 0.00341 | 1.8746864 | 30 | FABP5 | 0.00281 | −1.3844588 |
| 11 | XDH | 0.00345 | 2.4103457 | 31 | ALOX5 | 0.00753 | −1.0923645 |
| 12 | AKT1 | 0.00364 | 1.3787715 | 32 | SLC6A4 | 0.00958 | −1.6490666 |
| 13 | MMP13 | 0.00748 | 3.2412005 | 33 | CA2 | 0.0117 | −1.2531044 |
| 14 | PTGES | 0.00781 | 1.1341809 | 34 | BCHE | 0.0123 | −1.5660594 |
| 15 | CA13 | 0.00982 | 1.4324762 | 35 | HSD11B1 | 0.0125 | −1.3634651 |
| 16 | MMP9 | 0.0114 | 1.9071978 | 36 | PFKFB3 | 0.013 | −2.3139196 |
| 17 | MAPT | 0.0163 | 1.2303265 | 37 | AKR1C4 | 0.0138 | −1.0646393 |
| 18 | CCNB2 | 0.0163 | 1.1197655 | 38 | ESR1 | 0.0213 | −1.1750729 |
| 19 | PTPRF | 0.0253 | 1.1681767 | 39 | AR | 0.0267 | −1.0753623 |
| 20 | SHBG | 0.0398 | 1.1883309 |
FC fold change