Table 5.

Risk of Cirrhosis-Related Complications According to MELD3.0

	Unadjusted HR (95% CI)	p-value	Adjusted HR* (95% CI)	p-value	Adjusted HR† (95% CI)	p-value	Adjusted HR‡ (95% CI)	p-value
Cirrhosis-related complication	1.038 (1.030–1.046)	<0.001	1.039 (1.031–1.047)	<0.001	1.039 (1.031–1.048)	<0.001	1.033 (1.025–1.041)	<0.001
New onset or uncontrolled ascites	1.041 (1.029–1.053)	<0.001	1.041 (1.029–1.053)	<0.001	1.041 (1.029–1.053)	<0.001	1.040 (1.028–1.053)	<0.001
Gastroesophageal varix bleeding	1.008 (0.997–1.019)	0.178	1.005 (0.994–1.017)	0.361	1.006 (0.995–1.018)	0.270	1.006 (0.995–1.017)	0.301
Hepatorenal syndrome§	1.143 (1.106–1.180)	<0.001	1.145 (1.108–1.184)	<0.001	1.148 (1.110–1.186)	<0.001	1.149 (1.111–1.188)	<0.001
Hepatic encephalopathy	1.068 (1.054–1.081)	<0.001	1.078 (1.064–1.091)	<0.001	1.077 (1.064–1.091)	<0.001	1.077 (1.063–1.090)	<0.001

MELD3.0, Model for End-Stage Liver Disease 3.0; HR, hazard ratio; CI, confidence interval.

*Adjusted for age; ^†Adjusted for age and sex; ^‡Adjusted for age, sex, and etiology of liver disease; ^§Firth correction was applied for analyzing hepatorenal syndrome.