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. 2025 May 13;21(5):e70157. doi: 10.1002/alz.70157

FIGURE 3.

FIGURE 3

Sedentary time associations with longitudinal neurodegeneration and cognition. Plots include outliers. For naming and WAIS‐IV, higher values reflect better performance. Greater sedentary time related to smaller hippocampal volume (β = ‐0.1, p = 0.008), and worse naming (β = ‐0.001, p = 0.03), WAIS‐IV Coding (β = ‐0.003, p = 0.02), and D‐KEFS Number Sequencing (β = 0.01, p = 0.01) speed. Models remained significant when adjusting for MVPA. D‐KEFS, Delis–Kaplan Executive Function System; MVPA, moderate‐to‐vigorous physical activity; WAIS‐IV, Wechsler Adult Intelligence Scale ‐ fourth edition.