Table 4.
Main toxicities of immunotherapy combined with anlotinib
| Toxicity | Grades 1–2 | Grades 3 |
|---|---|---|
| Liver toxicity | 2 | 0 |
| Adrenocortical insufficiency | 1 | 0 |
| Hand-foot syndrome | 1 | 1 |
| Arthralgia | 1 | 0 |
| Pruritus | 1 | 0 |
| Rash | 2 | 0 |
| Diarrhea | 2 | 0 |
| Hemoptysis | 1 | 0 |
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