ACE2	Angiotensin-converting enzyme 2
BLI	Biolayer interferometry
CNN	Convolutional neural network
ΔG	Binding free energy
ΔH	Binding enthalpy
ITC	Isothermal titration calorimetry
KD	Dissociation constant
MD	Molecular dynamics
RBD	Receptor-binding domain
RBM	Receptor-binding motif
SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2
SPR	Surface plasmon resonance
TΔS	Entropic contribution to the binding free energy
VOC	Variants of concern
VOI	Variants of interest
WHO	World Health Organization
WT	Wild type