Table 5.

Change in Visual Acuity between Baseline and Visit at which Neovascular AMD was Identified, Stratified by Method Confirming the Event

Confirmation of Neovascular AMD	Device Arm Median (IQR) Change in VA from Baseline (letter score)	Standard Care Arm Median (IQR) Change in VA from Baseline (letter score)	Total Median (IQR) Change in VA from Baseline (letter score)	P Value
Investigator-identified event	N = 51 −4.0 (−11.0 to −1.0)	N = 30* −9.0 (−14.0 to −4.0)	N = 81* −7.0 (−12.0 to −2.0)	0.021
Reading center confirmation on FA and/or OCT	N = 41 −4.0 (−10.0 to −2.0)	N = 6 −10.0 (−14.0 to −4.0)	N = 67 −7.0 (−12.0 to −3.0)	0.008
Reading center confirmation on OCT	N = 37 −3.0 (−8.0 to −2.0)	N = 22 −9.0 (−13.0 to −4.0)	N = 59 −5.0 (−11.0 to −2.0)	0.005
Reading center confirmation on FA	N = 23 −4.0 (−11.0 to −3.0)	N = 19, −12.0 (−25.0 to −4.0)	N = 42 −8.0 (−13.0 to −3.0)	0.006

AMD = age-related macular degeneration; FA = fluorescein angiogram; IQR = interquartile range; VA = visual acuity.

^*Visual acuity not available in 1 eye.