Table 2.
Individual and combined diagnostic accuracy of serum P16ink4A and FOXP3 concentrations for the detection of cervical intraepithelial neoplasia and cervical cancer from healthy controls.
| Biomarker | CIN | CC | ||
|---|---|---|---|---|
| Percentage | 95% CI | Percentage | 95% CI | |
| FOXP3 | ||||
| Sensitivity | 32.22% | 25.40%–39.05% | 57.78% | 50.56%–64.99% |
| Specificity | 68.89% | 62.13%–75.65% | 68.89% | 62.13%–75.65% |
| P16ink4A | ||||
| Sensitivity | 50.00% | 42.70%–57.30% | 60.00% | 52.84%–67.16% |
| Specificity | 56.67% | 49.43%–63.91% | 55.56% | 48.30%–62.81% |
| Combination Of FOXP3 and P16ink4A | ||||
| Sensitivity | 18.89% | 13.17%–24.61% | 33.33% | 26.45%–40.22% |
| Specificity | 83.33% | 77.89%–88.78% | 83.33% | 77.89%–88.78% |
Abbreviations: CC, cervical cancer; CI, confidence interval; CIN, cervical intraepithelial neoplasia.