Table 2.
EQ-5D-3L utility index score at baseline and 6, 12, 18, and 24 months (France, 2015–2019).
| Baseline | M6 | M12 | M18 | M24 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Median | IQR | n | Median | IQR | n | Median | IQR | n | Median | IQR | n | Median | IQR | |
| Overall population | 177 | 0.89 | 0.80–1.00 | 125 | 0.80 | 0.80–0.89 | 108 | 0.80 | 0.64–0.89 | 97 | 0.80 | 0.73–0.89 | 81 | 0.80 | 0.73–0.91 |
| Randomization group | |||||||||||||||
| Supportive intervention | 88 | 0.89 | 0.80–0.91 | 64 | 0.80 | 0.78–0.89 | 56 | 0.80 | 0.69–0.89 | 51 | 0.80 | 0.64–0.89 | 43 | 0.80 | 0.64–0.91 |
| Control | 89 | 0.89 | 0.80–1.00 | 61 | 0.80 | 0.80–0.89 | 52 | 0.80 | 0.63–0.91 | 46 | 0.80 | 0.73–0.89 | 38 | 0.89 | 0.73–0.91 |
| Patient sex | |||||||||||||||
| Male | 79 | 0.89 | 0.80–0.91 | 57 | 0.80 | 0.80–0.89 | 57 | 0.80 | 0.63–0.89 | 45 | 0.80 | 0.73–0.91 | 37 | 0.80 | 0.73–0.91 |
| Female | 98 | 0.89 | 0.80–1.00 | 68 | 0.80 | 0.80–0.89 | 51 | 0.80 | 0.64–0.89 | 52 | 0.80 | 0.69–0.89 | 44 | 0.89 | 0.69–0.90 |
| Patient age, years | |||||||||||||||
| <80 | 123 | 0.89 | 0.80–1.00 | 87 | 0.80 | 0.80–0.89 | 81 | 0.80 | 0.64–0.89 | 67 | 0.80 | 0.64–0.89 | 59 | 0.80 | 0.64–0.91 |
| ≥80 | 54 | 0.84 | 0.80–0.91 | 38 | 0.80 | 0.75–0.89 | 27 | 0.80 | 0.64–0.89 | 30 | 0.80 | 0.80–0.89 | 22 | 0.80 | 0.80–0.89 |
| Patient disease | |||||||||||||||
| Neurodegenerative disease | 66 | 0.80 | 0.80–0.89 | 44 | 0.80 | 0.74–0.89 | 36 | 0.80 | 0.63–0.89 | 34 | 0.80 | 0.73–0.89 | 31 | 0.80 | 0.64–0.89 |
| Stroke/age-related macular degeneration | 21 | 0.91 | 0.89–1.00 | 14 | 0.89 | 0.58–0.91 | 12 | 0.89 | 0.84–0.91 | 14 | 0.84 | 0.73–0.89 | 11 | 0.89 | 0.73–0.89 |
| Cancer | 90 | 0.89 | 0.80–1.00 | 67 | 0.80 | 0.80–1.00 | 60 | 0.87 | 0.64–0.91 | 49 | 0.80 | 0.73–0.91 | 39 | 0.89 | 0.64–1.00 |
| Patient neurodegenerative disease | |||||||||||||||
| Yes | 66 | 0.80 | 0.80–0.89 | 44 | 0.80 | 0.74–0.89 | 36 | 0.80 | 0.63–0.89 | 34 | 0.80 | 0.73–0.89 | 31 | 0.80 | 0.64–0.89 |
| No | 111 | 0.89 | 0.80–1.00 | 81 | 0.89 | 0.80–0.91 | 72 | 0.89 | 0.69–0.91 | 63 | 0.80 | 0.73–0.91 | 50 | 0.89 | 0.73–1.00 |
| Caregiver sex | |||||||||||||||
| Female | 120 | 0.89 | 0.80–0.91 | 85 | 0.80 | 0.80–0.89 | 80 | 0.80 | 0.63–0.89 | 67 | 0.80 | 0.73–0.91 | 51 | 0.80 | 0.64–0.91 |
| Male | 57 | 0.89 | 0.73–1.00 | 40 | 0.84 | 0.77–0.89 | 28 | 0.89 | 0.64–0.89 | 30 | 0.80 | 0.64–0.89 | 30 | 0.89 | 0.80–0.91 |
| Caregiver age, years | |||||||||||||||
| <65 | 82 | 0.89 | 0.80–1.00 | 52 | 0.80 | 0.80–0.89 | 52 | 0.82 | 0.64–0.91 | 45 | 0.80 | 0.73–0.91 | 33 | 0.89 | 0.64–1.00 |
| ≥65 | 95 | 0.89 | 0.73–0.91 | 73 | 0.80 | 0.75–0.89 | 56 | 0.80 | 0.64–0.89 | 52 | 0.80 | 0.73–0.89 | 48 | 0.80 | 0.73–0.89 |
| Marital status, living situation | |||||||||||||||
| Married, common-law couple, civil partnerships | 149 | 0.89 | 0.80–0.91 | 103 | 0.80 | 0.80–0.89 | 89 | 0.80 | 0.64–0.89 | 82 | 0.80 | 0.73–0.89 | 70 | 0.80 | 0.73–0.91 |
| Other (single, separated, divorced, or widowed) | 28 | 0.88 | 0.80–1.00 | 22 | 0.80 | 0.80–0.89 | 19 | 0.80 | 0.49–0.91 | 15 | 0.80 | 0.80–0.91 | 11 | 0.89 | 0.64–1.00 |
| Caregiver–patient relationship (caregiver taking care of his/her) | |||||||||||||||
| Spouse | 117 | 0.89 | 0.80–0.91 | 86 | 0.80 | 0.80–0.89 | 73 | 0.80 | 0.64–0.89 | 64 | 0.80 | 0.73–0.89 | 57 | 0.80 | 0.73–0.89 |
| Mother/Father | 41 | 0.89 | 0.80–1.00 | 29 | 0.80 | 0.80–0.89 | 24 | 0.80 | 0.64–0.90 | 26 | 0.82 | 0.80–0.91 | 17 | 0.80 | 0.64–1.00 |
| Other (friend, neighbor, sister, etc.) | 19 | 0.91 | 0.89–1.00 | 10 | 0.84 | 0.80–0.89 | 11 | 0.89 | 0.64–1.00 | 7 | 0.80 | 0.64–0.91 | 7 | 0.89 | 0.51–0.91 |
| Professional situation | |||||||||||||||
| Professional activity | 41 | 0.89 | 0.80–1.00 | 27 | 0.80 | 0.80–1.00 | 25 | 0.84 | 0.80–0.91 | 26 | 0.80 | 0.80–0.91 | 20 | 0.84 | 0.73–1.00 |
| Retired | 122 | 0.89 | 0.80–0.91 | 88 | 0.80 | 0.78–0.89 | 74 | 0.80 | 0.64–0.89 | 65 | 0.80 | 0.73–0.89 | 57 | 0.89 | 0.73–0.91 |
| Other: sick leave, unemployment, job training, etc. | 14 | 0.80 | 0.58–0.89 | 10 | 0.80 | 0.51–0.80 | 9 | 0.64 | 0.51–0.80 | 6 | 0.71 | 0.37–0.80 | 4 | 0.56 | 0.49–0.72 |
| Household incomes, euros/month | |||||||||||||||
| < 800 | 6 | 0.80 | 0.64–0.89 | 4 | 0.58 | 0.26–0.84 | 3 | 0.80 | 0.15–0.91 | 3 | 1.80 | 0.36–0.80 | 3 | 0.80 | 0.64–0.94 |
| From 800 to 1,500 | 16 | 0.89 | 0.65–0.91 | 14 | 0.84 | 0.80–0.91 | 11 | 0.64 | 0.49–0.89 | 7 | 0.80 | 0.64–0.80 | 6 | 0.77 | 0.49–0.89 |
| From 1,501 to 3,000 | 86 | 0.89 | 0.80–0.91 | 62 | 0.80 | 0.80–0.89 | 52 | 0.80 | 0.64–0.89 | 54 | 0.80 | 0.80–0.89 | 40 | 0.89 | 0.77–0.91 |
| Up to 3,001 | 50 | 0.89 | 0.73–1.00 | 33 | 080 | 0.75–0.89 | 30 | 0.89 | 0.80–1.00 | 24 | 0.80 | 0.73–0.89 | 20 | 0.84 | 0.77–0.96 |
IQR, interquartile range; M, month; n, number.