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. 2025 Apr 30;12:1575363. doi: 10.3389/fmed.2025.1575363

TABLE 2.

MRI differences between pyogenic spondylitis, tuberculous spondylitis and fungal spondylitis.

Feature Fungal spondylitis Pyogenic spondylitis Tuberculous spondylitis
Location Lumbar Lumbar Thoracic
Number of affected vertebrae Usually involves two or more connected vertebrae Usually involves two connected vertebrae May involve skipping lesions (higher probability)
Degree of vertebral destruction Mild, often localized erosion Mild to moderate Severe, often > 50% destruction
Signal intensity of vertebrae T2WI typically shows the vertebrae as low signal, while STIR highlights the vertebrae with high signal. Vertebral high signal on T2WI, vertebral high signal on STIR Vertebral high signal on T2WI, vertebral high signal on STIR
Paraspinal abscess Thick, irregular abscess wall Thick Thin, regular abscess wall
Vertebral abscess Rare Rare Common
Intradiscal abscess Rare Common Rare

STIR, short tau inversion recovery.