Table 3.
The relationship between THYCA-QOL summary score, EORTC QLQ-C30 summary score, and patient characteristics.
| THYCA-QOL summary score (Mean ± SD) | P | EORTC QLQ-C30 summary score (Mean ± SD) | P | |
|---|---|---|---|---|
| Gender | <0.001 | 0.015 | ||
| Men | 16.96 ± 10.66 | 84.88 ± 12.89 | ||
| Women | 21.01 ± 11.52 | 82.09 ± 13.87 | ||
| Age at diagnosis (years) | 0.006 | 0.660 | ||
| 18-44 | 21.30 ± 11.79 | 82.26 ± 13.78 | ||
| 45-59 | 18.93 ± 10.88 | 82.94 ± 13.89 | ||
| ≥60 | 16.71 ± 9.63 | 84.48 ± 11.48 | ||
| Follow- up duration (months) | 0.405 | <0.001 | ||
| ≤6 | 20.41 ± 11.59 | 66.07 ± 13.79 | ||
| 7-24 | 19.99 ± 11.42 | 86.29 ± 10.57 | ||
| 25-60 | 20.29 ± 11.56 | 87.50 ± 9.46 | ||
| >60 | 22.85 ± 11.01 | 86.48 ± 9.82 | ||
| BMI (kg/m2) | 0.052 | 0.027 | ||
| <24 | 20.28 ± 11.22 | 82.19 ± 13.90 | ||
| 24-28 | 19.50 ± 11.42 | 84.03 ± 13.47 | ||
| ≥28 | 22.91 ± 12.77 | 80.41 ± 13.20 | ||
| Ethnicity | 0.282 | 0.938 | ||
| Han | 20.06 ± 11.31 | 82.53 ± 13.84 | ||
| Other | 21.52 ± 12.27 | 82.89 ± 13.20 | ||
| Marital status | 0.949 | 0.942 | ||
| Married | 20.21 ± 11.34 | 82.77 ± 13.36 | ||
| Single* | 20.97 ± 12.59 | 81.00 ± 16.65 | ||
| Employment status | 0.609 | 0.571 | ||
| Employed | 20.46 ± 11.67 | 82.75 ± 13.54 | ||
| Unemployed | 19.75 ± 10.81 | 82.07 ± 14.34 | ||
| Chronic disease | 0.804 | 0.524 | ||
| Yes | 20.23 ± 11.75 | 82.11 ± 13.59 | ||
| No | 20.30 ± 11.41 | 82.70 ± 13.77 | ||
| Residence | 0.633 | 0.099 | ||
| Urban | 20.23 ± 11.50 | 82.83 ± 13.73 | ||
| Rural | 20.78 ± 11.26 | 80.70 ± 13.66 | ||
| Smoking | 0.131 | 0.520 | ||
| Yes | 18.59 ± 11.39 | 83.46 ± 13.54 | ||
| No | 20.43 ± 11.47 | 82.52 ± 13.75 | ||
| Drinking | 0.281 | 0.083 | ||
| Yes | 18.28 ± 12.26 | 87.23 ± 11.56 | ||
| No | 20.35 ± 11.45 | 82.46 ± 13.77 | ||
| Family history of thyroid cancer | 0.682 | 0.628 | ||
| Yes | 20.95 ± 11.08 | 81.35 ± 14.40 | ||
| No | 20.26 ± 11.49 | 82.65 ± 13.70 | ||
| Type of thyroidectomy | 0.010 | 0.225 | ||
| Total thyroidectomy | 21.25 ± 11.96 | 83.34 ± 13.15 | ||
| Partial thyroidectomy† | 19.14 ± 10.75 | 81.69 ± 14.36 | ||
| Central lymph node dissection | 0.263 | 0.074 | ||
| Bilateral | 20.91 ± 11.97 | 83.57 ± 13.09 | ||
| Single | 19.65 ± 10.88 | 81.62 ± 14.27 | ||
| No | 16.45 ± 9.07 | 70.48 ± 19.66 | ||
| Lateral neck lymph node dissection | 0.742 | 0.676 | ||
| Yes | 20.72 ± 11.85 | 83.41 ± 12.99 | ||
| No | 20.23 ± 11.41 | 82.46 ± 13.85 | ||
| Parathyroid autotransplantation | 0.657 | 0.995 | ||
| Yes | 20.64 ± 11.94 | 82.24 ± 14.65 | ||
| No | 20.23 ± 11.39 | 82.65 ± 13.56 | ||
| T | 0.003 | 0.754 | ||
| T1 | 19.77 ± 11.10 | 82.35 ± 14.00 | ||
| T2 | 18.85 ± 11.23 | 85.39 ± 11.46 | ||
| T3 | 25.17 ± 13.19 | 83.14 ± 12.31 | ||
| T4 | 21.98 ± 13.17 | 84.16 ± 12.72 | ||
| N | 0.269 | 0.803 | ||
| N0 | 19.85 ± 11.55 | 82.10 ± 14.30 | ||
| N1a | 20.82 ± 11.07 | 83.20 ± 12.86 | ||
| N1b | 21.03 ± 12.21 | 83.31 ± 13.29 | ||
| TNM | 0.445 | 0.777 | ||
| I | 20.36 ± 11.49 | 82.53 ± 13.76 | ||
| II | 19.09 ± 10.98 | 83.88 ± 13.70 | ||
| III | 13.62 ± 10.53 | 88.57 ± 5.89 | ||
| Hashimoto thyroiditis | 0.912 | 0.044 | ||
| Yes | 20.11 ± 11.06 | 80.74 ± 14.70 | ||
| No | 20.36 ± 11.62 | 83.26 ± 13.31 | ||
| Multifocality | 0.698 | 0.254 | ||
| Yes | 20.18 ± 11.54 | 83.48 ± 13.02 | ||
| No | 20.36 ± 11.43 | 82.04 ± 14.14 | ||
| Recurrence risk | 0.029 | 0.685 | ||
| Low risk | 19.91 ± 11.31 | 82.53 ± 13.91 | ||
| Intermediate risk | 21.46 ± 11.93 | 81.97 ± 13.32 | ||
| High risk | 24.26 ± 12.40 | 84.75 ± 11.40 | ||
| Current TSH level (μ IU/mL) | 0.914 | 0.938 | ||
| ≤0.5 | 20.05 ± 11.16 | 82.60 ± 13.40 | ||
| 0.5-2 | 20.20 ± 11.13 | 82.56 ± 13.81 | ||
| >2 | 21.14 ± 13.24 | 82.65 ± 14.22 | ||
| Biochemical incomplete response | 0.286 | 0.356 | ||
| Yes | 23.17 ± 13.89 | 86.23 ± 9.07 | ||
| No | 20.20 ± 11.38 | 82.47 ± 13.84 | ||
| Structural incomplete response | 0.946 | 0.445 | ||
| Yes | 21.56 ± 15.74 | 84.67 ± 13.09 | ||
| No | 20.26 ± 11.36 | 82.54 ± 13.75 | ||
| Recurrence reoperation | 0.045 | 0.018 | ||
| Yes | 29.64 ± 20.34 | 74.95 ± 15.61 | ||
| No | 20.09 ± 11.14 | 82.75 ± 13.65 | ||
| RAI treatments | 0.031 | 0.829 | ||
| Yes | 23.62 ± 12.07 | 82.91 ± 12.20 | ||
| No | 20.08 ± 11.40 | 82.57 ± 13.83 | ||
| Permanent hypoparathyroidismΔ | 0.048 | 0.292 | ||
| Yes | 29.98 ± 17.95 | 84.08 ± 10.70 | ||
| No | 20.05 ± 11.18 | 86.75 ± 10.18 | ||
| Calcium or/and Vitamin D intake | 0.076 | 0.965 | ||
| Yes | 21.32 ± 11.84 | 82.81 ± 13.31 | ||
| No | 19.82 ± 11.27 | 82.49 ± 13.93 | ||
| Postoperative complaints | <0.001 | <0.001 | ||
| 0 | 19.70 ± 11.07 | 83.46 ± 13.38 | ||
| 1 | 24.52 ± 10.13 | 74.49 ± 13.36 | ||
| ≥2 | 35.90 ± 18.51 | 64.62 ± 11.49 |
*Including divorced, widowed and never married.
†Including isthmectomy and lobectomy.
ΔThe incidence of permanent hypoparathyroidism was assessed based on 689 DTC patients with a postoperative follow-up period exceeding 6 months.
BMI, body mass index; TSH, thyrotropin; RAI, radioiodine.