Table 2. Maternal characteristics, HBsAg and HBsAb positivity in infants, and associated risk factors based on PVST results..
| Variable | No. with PVST ( N =3,243) | HBsAg status | HBsAb status | |||
|
No. positive
(N=26) |
Rate (%) |
No. positive (N=3,147) |
Rate (%) | |||
| Univariate analysis results: * HbsAg group: P<0.05; † HBsAb group: P<0.05. Abbreviation: PVST=post vaccination serological testing; HBV=hepatis B virus; DNA=deoxyribonucleic acid; HBsAg=hepatitis B surface antigen; HBsAb=hepatitis B surface antibody; HepB=hepatitis B vaccine; HBIG=hepatitis B immunoglobulin; HBeAg=hepatitis B e-antigen. | ||||||
| Maternal age (years)* | ||||||
| 15–24 | 215 | 2 | 0.9 | 210 | 97.7 | |
| 25–29 | 963 | 14 | 1.4 | 928 | 96.4 | |
| 30–34 | 1,340 | 6 | 0.5 | 1,299 | 96.9 | |
| 35–50 | 725 | 4 | 0.6 | 710 | 97.9 | |
| Maternal ethnicity | ||||||
| Han | 3,115 | 25 | 0.8 | 3,024 | 97.1 | |
| Other | 128 | 1 | 0.8 | 123 | 96.1 | |
| Maternal education | ||||||
| Junior high school and below | 2,187 | 13 | 0.6 | 2,117 | 96.8 | |
| High school and above | 1,056 | 13 | 1.2 | 1,030 | 97.5 | |
| Maternal occupation† | ||||||
| Farmers | 881 | 9 | 1.0 | 840 | 95.3 | |
| Other | 2,362 | 17 | 0.7 | 2,307 | 97.7 | |
| HBV infected time (years) | ||||||
| ≤5 | 1,410 | 9 | 0.6 | 1,373 | 97.4 | |
| >5 | 1,833 | 17 | 0.9 | 1,774 | 96.8 | |
| Maternal HBV DNA tested† | ||||||
| Yes | 469 | 4 | 0.9 | 462 | 98.5 | |
| No | 2,761 | 22 | 0.8 | 2,672 | 96.8 | |
| Maternal receipt of antiviral therapy during pregnancy | ||||||
| Yes | 202 | 2 | 1.0 | 197 | 97.5 | |
| No | 3,040 | 24 | 0.8 | 2,949 | 97.0 | |
| Maternal HBeAg status during pregnancy* | ||||||
| Negative | 2,420 | 5 | 0.2 | 2,370 | 97.9 | |
| Positive | 745 | 19 | 2.6 | 704 | 94.5 | |
| Unknown | 77 | 2 | 2.6 | 72 | 93.5 | |
| Received HBIG during pregnancy† | ||||||
| Yes | 41 | 1 | 2.4 | 40 | 97.6 | |
| No | 2,950 | 24 | 0.8 | 2,860 | 97.0 | |
| Unknown | 248 | 1 | 0.4 | 243 | 98.0 | |
| Infant sex | ||||||
| Male | 1,687 | 15 | 0.9 | 1,639 | 97.2 | |
| Female | 1,554 | 11 | 0.7 | 1,506 | 96.9 | |
| Birth weight (kg) | ||||||
| ≥2.50 | 3,121 | 26 | 0.8 | 3,025 | 96.9 | |
| <2.50 | 120 | 0 | 0.0 | 120 | 100 | |
| Pregnancy duration (weeks) | ||||||
| ≥37 | 3,058 | 26 | 0.9 | 2,965 | 97.0 | |
| <37 | 183 | 0 | 0.0 | 180 | 98.4 | |
| Maternal parity | ||||||
| 1 | 1,042 | 10 | 1.0 | 1,011 | 97.0 | |
| 2 | 1,646 | 13 | 0.8 | 1,599 | 97.1 | |
| ≥3 | 552 | 3 | 0.5 | 534 | 96.7 | |
| Mode of delivery | ||||||
| Vaginal delivery | 1,639 | 14 | 0.9 | 1,598 | 97.5 | |
| Caesarean section | 1,603 | 12 | 0.8 | 1,548 | 96.6 | |
| Timely receipt of HBIG | ||||||
| No | 60 | 1 | 1.7 | 59 | 98.3 | |
| Yes | 3,183 | 25 | 0.8 | 3,088 | 97.0 | |
| Timely receipt of first HepB dose | ||||||
| No | 181 | 3 | 1.7 | 176 | 97.2 | |
| Yes | 3,062 | 23 | 0.8 | 2,971 | 97.0 | |