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. 2025 Mar 31;63(5):e01807-24. doi: 10.1128/jcm.01807-24

TABLE 5.

Estimates of the specificity of each test adjusting for conditional dependence (median, 95% credible interval) and with correction for sampling

Specificity for the presence of C. difficile bacterium Specificity for the presence of C. difficile toxin gene Specificity for the presence of C. difficile toxin
Culture 1.00 (1.00–1.00) 0.96 (0.96–0.97) 0.93 (0.92–0.94)
VIDAS GDH 0.99 (0.98–1.00) 0.95 (0.94–0.96) 0.91 (0.90–0.93)
NAAT 0.99 (0.99–0.99) 0.99 (0.99–0.99) 0.95 (0.94–0.97)
Toxigenic culture 1.00 (1.00–1.00) 1.00 (0.99–1.00) 0.96 (0.95–0.98)
SIMOA A 0.98 (0.97–0.98) 0.98 (0.97–0.98) 0.98 (0.97–0.98)
SIMOA B 0.99 (0.99–0.99) 0.99 (0.98–0.99) 0.99 (0.98–0.99)
CCNA 1.00 (1.00–1.00) 1.00 (1.00–1.00) 1.00 (1.00–1.00)
VIDAS toxin EIA 0.99 (0.98–0.99) 0.98 (0.98, 0.98) 0.99 (0.98–0.99)