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. 2002 Mar;66(1):39–63. doi: 10.1128/MMBR.66.1.39-63.2002

FIG. 2.

FIG. 2.

Mechanisms by which a single gene can give rise to multiple gene products. Multiple protein isoforms can be generated by RNA processing when RNA is alternatively spliced or edited to form mature mRNA. mRNA, in turn, can be regulated by stability and efficiency of translation. Proteins can be regulated by additional mechanisms, including posttranslational modification, proteolysis, or compartmentalization.