Table 3.
Binary logistic regression analysis of association between mid-pregnancy plasma glucose levels and adverse pregnancy outcomes.
| Variable | n (%) | Crude | Adjusted | ||
|---|---|---|---|---|---|
| OR (95%CI) | P | OR (95%CI) | P | ||
| GDM | <0.001 | <0.001 | |||
| No | 37562 (76.8) | 1 (Ref) | 1 (Ref) | ||
| Yes | 11338 (23.2) | 1.26 (1.20-1.32) | 1.19 (1.14-1.25) | ||
| OGTT 0h | <0.001 | <0.001 | |||
| <5.1 mmol/L | 43547 (89.1) | 1 (Ref) | 1 (Ref) | ||
| ≥5.1 mmol/L | 5353 (10.9) | 1.24 (1.16-1.32) | 1.18 (1.11-1.26) | ||
| OGTT 1h | <0.001 | <0.001 | |||
| <10 mmol/L | 43626 (89.2) | 1 (Ref) | 1 (Ref) | ||
| ≥10 mmol/L | 5274 (10.8) | 1.36 (1.27-1.45) | 1.28 (1.20-1.37) | ||
| OGTT 2h | <0.001 | <0.001 | |||
| <8.5 mmol/L | 44198 (90.4) | 1 (Ref) | 1 (Ref) | ||
| ≥8.5 mmol/L | 4702 (9.6) | 1.33 (1.24-1.42) | 1.24 (1.16-1.33) | ||
| OGTT groups | |||||
| Group 1 | 37562 (76.8) | 1 (Ref) | 1 (Ref) | ||
| Group 2 | 3908 (8.0) | 1.18 (1.10-1.28) | <0.001 | 1.14 (1.06-1.24) | <0.001 |
| Group 3 | 5985 (12.2) | 1.24 (1.17-1.32) | <0.001 | 1.18 (1.10-1.25) | <0.001 |
| Group 4 | 1445 (3.0) | 1.56 (1.39-1.74) | <0.001 | 1.42 (1.26-1.59) | <0.001 |
| P for trend | <0.001 | <0.001 | |||
GDM, gestational diabetes mellitus; OGTT, oral glucose tolerance test. Group 1 represents normal plasma glucose at 0h, 1h and 2h; Group 2 represents abnormal plasma glucose at 0h, but normal plasma glucose at 1h and 2h; Group 3 represents normal plasma glucose at 0h, but abnormal plasma glucose at 1h or 2h; Group 4 represents abnormal plasma glucose at 0h, 1h or 2h. Adjusted for maternal age, gravidity, parity, assisted reproduction, gestational hypertension, gestational thyroid disorders, delivery mode and infant sex. Bold represents P values less than 0.05.