Table 2.
MG-ADL and QMG baseline mean values and differences of the means during a 26-week follow-up
| Baseline | Week 2 | Week 10 | Week 18 | Week 26 | |
|---|---|---|---|---|---|
| MG-ADL§ | 9.37 | −4 | −5.29 | −5.91 | −5.58 |
| (SD) | −3.28 | −2.34 | −2.86 | −2.56 | −2.96 |
| 95%CI | 7.99–10.76 | −4.98; −3.01 | −6.50; −4.08 | −7.00; −4.83 | −6.83; −4.33 |
| Median (IQR) | 8.0 (6.0;12.0) | −3.0 (−5.75; −2.00) | −5.0 (−6.0; −4.0) | −6.0 (−7.5; −4.25) | −5.5 (−7.75; −3.25) |
| MG-ADL responders ^ | 17/24 | 19/24 | 17/22 | 17/21 | |
| (%) | −70.8 | −79.2 | −77.3 | −81 | |
| QMG§ | 14.75 | −4.5 | −5.75 | −6.21 | −6.62 |
| (SD) | −4.64 | −2.99 | −2.95 | −3.23 | −3.63 |
| 95%CI | 12.79–16.71 | −5.76; −3.23 | −6.99; −4.50 | −7.57; −4.84 | −8.15; −5.09 |
| Median (IQR) | 14.5 (11.25–17.0) | −4.5 (−7.0; −2.25) | −5.5 (−8.0; −3.25) | −6.0 (−8.8; −4.0) | −7.0 (−8.0; −4.0) |
| QMG responders ^ | Dec-24 | 15/24 | 14/22 | 14/21 | |
| (%) | −50 | −62.5 | −63.6 | −66.7 |
Note: Values are expressed as mean ± SD and 95% CI
§ Mean score at baseline and mean difference with respect to baseline during follow-up
° Mean dosage at baseline and mean dosage change during follow-up
MG-ADL Myasthenia Gravis Activity of Daily Living, QMG Quantitative Myasthenia Gravis, MGC Myasthenia Gravis Composite
^ MG-ADL responders: patients with reduction in MG-ADL score of at least 3 points from baseline; QMG responders: patients with reduction in QMG score of at least 5 points from baseline