TABLE 1.
Transmembrane proteins in X. fastidiosa, 18 other prokaryotes, and S. cerevisiaea
| Species | No. of ORFs | TMb
|
% of ORFs with N TMSs
|
Major transporters
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | % | 0 | 1 | 2-3 | 4-6 | 7-9 | 10+ | ≥ 4 | No. | % of total ORFs | No./Mb of DNA | ||
| Mycoplasmas | |||||||||||||
| Mycoplasma genitalium | 480 | 185 | 38.5 | 61.5 | 21.5 | 7.1 | 5.0 | 3.1 | 1.9 | 10.0 | 20 | 4.3 | 35 |
| Mycoplasma pneumoniae | 677 | 221 | 32.6 | 67.4 | 18.2 | 5.5 | 5.5 | 1.9 | 1.6 | 9.0 | 22 | 3.3 | 27 |
| Gram-positive bacteria | |||||||||||||
| Bacillus subtilis | 4,100 | 1,349 | 32.9 | 67.1 | 13.4 | 6.3 | 6.0 | 4.0 | 3.3 | 13.3 | 265 | 6.6 | 63 |
| Mycobacterium tuberculosis | 3,918 | 1,644 | 42.0 | 58.0 | 22.9 | 10.1 | 4.7 | 1.9 | 2.4 | 9.0 | 113 | 2.9 | 26 |
| Gram-negative bacteria | |||||||||||||
| Escherichia coli | 4,289 | 1,445 | 33.7 | 66.3 | 15.2 | 5.5 | 5.0 | 4.2 | 3.7 | 12.9 | 304 | 7.1 | 66 |
| Haemophilus influenzae | 1,709 | 527 | 30.8 | 69.2 | 15.4 | 3.8 | 5.4 | 3.3 | 2.9 | 11.6 | 95 | 5.7 | 52 |
| Helicobacter pylori | 1,566 | 504 | 32.2 | 67.8 | 18.3 | 4.9 | 4.8 | 1.9 | 2.4 | 9.1 | 56 | 3.6 | 34 |
| Rickettsia prowazekii | 834 | 365 | 43.8 | 56.2 | 22.3 | 8.5 | 5.0 | 4.1 | 3.8 | 12.9 | 38 | 4.6 | 34 |
| Chlamydia trachomatis | 894 | 362 | 40.5 | 59.5 | 20.8 | 9.8 | 4.9 | 3.2 | 1.7 | 9.8 | 30 | 3.4 | 29 |
| Xylella fastidiosa | 2,830 | 957 | 33.8 | 66.1 | 21.7 | 6.1 | 3.3 | 1.3 | 1.4 | 6.0 | 75 | 2.7 | 28 |
| Spirochetes | |||||||||||||
| Borrelia burgdorferi | 850 | 357 | 42.0 | 58.0 | 23.5 | 7.4 | 6.2 | 3.2 | 1.6 | 11.0 | 36 | 4.2 | 25 |
| Treponema pallidum | 1,031 | 408 | 39.6 | 60.4 | 22.3 | 7.9 | 5.3 | 3.1 | 1.0 | 9.4 | 35 | 3.4 | 31 |
| Cyanobacterium | |||||||||||||
| Synechocystis sp. strain PCC6803 | 3,169 | 1,214 | 38.3 | 61.7 | 20.3 | 8.1 | 5.3 | 2.7 | 2.0 | 10.0 | 102 | 3.2 | 29 |
| Deep-branching bacteria | |||||||||||||
| Aquifex aeolicus | 1,522 | 468 | 30.7 | 69.3 | 16.3 | 4.3 | 5.6 | 2.6 | 2.0 | 10.2 | 44 | 2.9 | 28 |
| Thermotoga maritima | 1,846 | 645 | 34.9 | 65.1 | 18.6 | 5.4 | 6.7 | 2.8 | 1.4 | 10.9 | 86 | 4.7 | 46 |
| Archaea | |||||||||||||
| Methanococcus jannaschii | 1,715 | 526 | 30.7 | 69.3 | 17.3 | 5.7 | 4.5 | 1.8 | 1.3 | 7.6 | 42 | 2.4 | 25 |
| Methanobacterium thermoautotrophicum | 1,869 | 569 | 30.4 | 69.6 | 15.9 | 5.5 | 5.4 | 2.5 | 1.3 | 9.2 | 45 | 2.4 | 26 |
| Archeoglobus fulgidus | 2,407 | 772 | 32.1 | 69.9 | 17.0 | 5.5 | 4.6 | 3.2 | 1.7 | 9.5 | 71 | 2.9 | 33 |
| Pyrococcus horikoshii | 2,064 | 794 | 38.5 | 61.5 | 20.0 | 8.6 | 5.7 | 2.4 | 1.8 | 9.9 | 66 | 3.2 | 38 |
| Eukaryote | |||||||||||||
| Saccharomyces cerevisiae | 6,315 | 1,738 | 27.5 | 72.5 | 15.4 | 5.3 | 2.2 | 2.6 | 2.1 | 6.9 | 258 | 4.2 | 22 |
a
Data for X. fastidiosa, 18 other fully sequenced prokaryotes (previously analyzed by Paulsen et al. [31]), and S. cerevisiae (previously analyzed by Paulsen et al. [30]) were calculated with PSORT (25) as described in the text.
b
TM, transmembrane proteins (proteins with ≥1 TMS), given as number and as a percentage of all ORFs.