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TRT sensitizes “cold” murine tumor models to ICI. Tumor volume and survival in 4T1 breast cancer (A–C) and NXS2 neuroblastoma (D–F) in mice receiving 200 μg of CTLA-4 (C4, 3x) with or without 50 μCi (1.85 MBq) of 90Y-NM600 or saline control (vehicle only, VO) (n = 5–6 each). (Adapted with permission of ( 17 ).)
