Table 2.
Radiologic findings of cohort
|
Non-coal miners (n=194) |
Coal miners (n=362) | p-value | |||
|---|---|---|---|---|---|
|
Never smokers (n=46) |
Ever-smokers (n=148) |
Never smokers (n=124) |
Ever-smokers (n=238) |
||
| ILD patternsa | |||||
| Simple CWP, % | 0 | 0 | 32.3 | 34.5 | .67 |
| Complicated CWP, % | 0 | 0 | 28.2 | 19.7 | .07 |
| Any ILD, not including RB-ILD, % | 0 | 16.2 | 14.5 | 34.9 | <.01a |
| UIP % | 0 | 0.7 | 2.4 | 2.5 | .42 |
| Probable UIP % | 0 | 1.4 | 0.8 | 5.0 | .03 |
| NSIP % | 0 | 0.7 | 4.8 | 6.7 | .01 |
| RB-ILD (including small opacities) % | 0 | 3.4 | 25.0 | 12.3 | <.01a |
| DIP % | 0 | 2.0 | 0 | 8.0 | <.01a |
| CPFE % | 0 | 2.0 | 0.8 | 16.0 | <.01a |
| Organizing pneumonia % | 0 | 2.7 | 0.8 | 0.8 | .43 |
| Asbestosis % | 0 | 0 | 2.4 | 0.8 | .17 |
| Other/unclassifiable % | 0 | 4.1 | 2.4 | 1.7 | .25 |
| ILA patterns | 36.9 | 43.2 | 29.8 | 34.0 | .12 |
| CL-GGO % | 13.0 | 15.5 | 8.9 | 6.3 | .02 |
| SPR % | 17.4 | 17.6 | 8.1 | 11.8 | .09 |
| Mixed CL-GGO+SPR % | 10.9 | 11.5 | 17.7 | 21.0 | .07 |
| Non-emphysematous cysts % | 10.9 | 7.4 | 8.1 | 8.4 | .91 |
| Traction bronchiectasis/bronchiolectasis % | 21.7 | 26.3 | 13.7 | 18.5 | .06 |
| Any Emphysema | 13.0 | 87.8 | 29.0 | 77.7 | <.01a |
| Centrilobular % | 10.9 | 79.7 | 16.9 | 71.0 | <.01a |
| Paraseptal % | 2.2 | 34.5 | 3.2 | 53.4 | <.01a |
| Panacinar % | 0 | 8.1 | 0.8 | 9.7 | <.01a |
| Bullous % | 0 | 4.1 | 2.4 | 21.4 | <.01a |
| Cicatricial % | - | - | 18.6 | 15.1 | .40 |
| Pleural plaque/thickening % | 0 | 5.4 | 14.5 | 16.8 | <.01a |
| Dilated main pulmonary artery (ratio PA/Aorta >0.9), % | 15.2 | 18.9 | 23.4 | 24.8 | .35 |
CL centrilobular, CPFE combined pulmonary fibrosis emphysema, CWP Coal-workers’ pneumoconiosis, DIP Desquamative interstitial pneumonia, GGO ground glass opacity, ILD interstitial lung disease; NSIP nonspecific interstitial pneumonia, RB respiratory bronchiolitis, SPR subpleural reticular changes, UIP usual interstitial pneumonia
aSignificant p-value with adjusted α=<.016 as per Bonferroni correction