Table 2.

List of factors, secretion of which is up- or dawn-regulated in reactive States of microglia and astrocytes

Protein	Density
	Microglia		Astrocytes
	normal	reactive	normal	reactive
ICAM-1	4033 ± 88 *	1005 ± 80	1009 ± 5.5	993 ± 58
IL-1a	105 ± 6	4133 ± 145	105 ± 4.4	301 ± 57
IL-1b	200 ± 5.8	2533 ± 260	107 ± 4.7	205 ± 3.8
IL-1ra	103 ± 6.7	3900 ± 295	96 ± 7.2	169 ± 11
IL-6	140 ± 5.4	3511 ± 119	120 ± 2.9	3121 ± 104
IL-12	105 ± 5.8	155 ± 7.6	103 ± 5.8	2047 ± 33
IL-16	3033 ± 202	1993 ± 121	201 ± 15	305 ± 15
CXCL10	121 ± 2.6	1507 ± 57	130 ± 5.8	153 ± 6.1
CXCL12	136 ± 6.0	317 ± 11.9	110 ± 6.2	2200 ± 57
CXCL1	1026 ± 17	4512 ± 261	113 ± 21	2133 ± 88
CCL2	139 ± 5.9	3834 ± 88	135 ± 7.6	1932 ± 33
CCL3	151 ± 10	3153 ± 129	141 ± 4.5	210 ± 11
CCL5	140 ± 5.8	4241 ± 83	121 ± 7.3	216 ± 3.2
CCL12	111 ± 3.7	190 ± 5.6	111 ± 8.7	2217 ± 124
CCL4	210 ± 5.7	234 ± 8.6	131 ± 6.0	1099 ± 57
TNF-a	153 ± 5.5	2111 ± 57	116 ± 2.9	213 ± 2.6
TIMP-1	1007 ± 8.8	1196 ± 98	1003 ± 54	613 ± 40

^* Bold font used for secreted factors that were found to be up- or downregulated in reactive states relative to homeostatic states with high statistical significance