Figure 6.

Core T cell-associated genes demonstrate significant correlation with immune cell populations. (A) GO enrichment analysis of core genes showing significant pathways related to T cell function. Left bars indicate gene sets, with bar lengths representing gene ratios. Circle size indicates term ratio, and color gradient shows gene ratio. (B) KEGG pathway enrichment analysis highlighting involvement in hematopoietic and immune-related pathways. Circle size and color coding follow the same scheme as in (A). (C) Correlation heatmap between hub genes and immune cell populations based on XCell algorithm. Color intensity indicates correlation strength (red = positive, blue = negative); asterisks denote statistical significance (*P < 0.05, **P < 0.01). (D) Correlation heatmap between hub genes and immune cell populations based on Cibersort algorithm, showing distinct correlation patterns particularly with T cell subsets.