Table 1.

Sequence parameters

Sequence	TR/ms	TE/ms	Flip angle/°	Reconstructed FOV/mm	Reconstructed matrix
Ventilation imaging	3.2	1.6	~10	384 × 384 × 384	96 × 96 × 96
Dissolved-phase imaging	18	Echo train 1: 0.61/2.23/3.85 Echo train 2: 1.42/3.04	21 (dissolved)/0.4 (gas)	320 × 320 × 320	48 × 48 × 48
Fixed-TR dynamic spectroscopy	36	1.2	60	n/a	n/a
CSSR	Variable	0.7	~27 (excitation using maximum RF power)	n/a	n/a
Diffusion-weighted imaging	57	41.6	7.4	400 × 400 × 240	64 × 64 × 6

The sequence parameters for dissolved-phase imaging are comparable to those previously established for multi-echo techniques and to ¹²⁹Xe clinical trial consortium recommendations for multi-site trials [15, 28]. Compared to the recommendations, ventilation imaging uses a radial trajectory facilitating acceleration. Diffusion-weighted imaging uses shorter diffusion times to facilitate the estimation of surface-volume ratio. The impact of frequency-selective excitation in fixed-TR dynamic spectroscopy on dissolved-phase ratios is assessed in the supplemental material