Table 2.
Maternal and neonatal outcomes between pregnant women with and without BA.5 infection.
| Puerpera with COVID-19 (n=24) |
Puerpera without COVID-19 (n=105) |
P | |
|---|---|---|---|
| Maternal outcomes | |||
| Maternal age, median(P25-P75), years | 31(28.80-33.00) | 30(27-33) | 0.095 |
| Reproductive history | |||
| G | 3 (2-4) | 2 (1-4) | 0.434 |
| P | 1 (0-1) | 1 (0-1) | 0.843 |
| BMI (kg/m2) | 25.4 (24.10-26.80) | 26.5 (24.80-28.50) | 0.070 |
| Comorbidity, n(%) | |||
| Hypertension | 3 (12.50) | 3 (2.90) | 0.078 |
| Diabetes | 2 (8.30) | 13 (12.40) | 0.736 |
| Pregnancy risk & | |||
| Green (low) | 0 (0) | 35 (33.30) | – |
| Yellow (moderate) | 0 (0) | 2 (1.90) | – |
| Orange (relatively high) | 0 (0) | 35 (33.30) | – |
| Pink (high) | 0 (0) | 29 (27.60) | – |
| Red (extremely high) | 0 (0) | 3 (2.90) | – |
| Purple (with infectious diseases) | 17 (70.80) | 0 (0) | – |
| Purple + orange | 4 (16.70) | 1 (1.00) | – |
| Purple+red | 3 (12.50) | 0 (0) | – |
| Prenatal symptoms | |||
| Celialgia | 15 (62.50) | 55 (52.40) | 0.369 |
| Uterine contraction | 18 (75.00) | 59 (56.20) | 0.090 |
| Uterine bleeding | 2 (8.30) | 32 (30.50) | 0.038 |
| Delivery approaches | |||
| Cesarean delivery | 16(66.67) | 56 (53.33) | 0.235 |
| Vaginal delivery | 8(33.33) | 49 (46.67) | |
| Delivery status | |||
| Intrapartum hemorrhage-cesarean section | 300 (200-300) | – | – |
| Cesarean section Operation duration (min) | 58 (50.75-71.50) | – | – |
| Intrapartum hemorrhage-eutocia | 150 (100-150) | – | – |
| Intrapartum hemorrhage-all | 200 (150-300) | – | – |
| Postpartum symptom | |||
| Abnormal postpartum hemorrhage | 0 (0) | – | – |
| Abnormal prenatal abdominal pain | 0 (0) | – | – |
| Abnormal postpartum vaginal bleeding | 0 (0) | – | – |
| Discharge status | |||
| Steady | 24 (100) | 105 (100) | – |
| Admitted to ICU | 24 (100) | – | – |
| Neonatal outcomes | |||
| Gestational age at delivery, weeks | 38(36-39) | 38(38-39) | 0.049 |
| Full-term | 19 (79.20) | 92 (87.60) 13 (12.4) 2 (1.9) 105 (100) |
0.281 |
| Premature delivery | 5 (20.80) | 13 (12.40) 2 (1.9) 105 (100) |
|
| Intrauterine hypoxia | 3 (12.50) | 2 (1.90) 2 (1.9) 105 (100) |
0.015 |
| Oxygen therapy | 24 (100) | 105 (100) 13 (12.4) 2 (1.9) 105 (100) |
>0.999 |
| Amniotic fluid | |||
| Amniotic fluid clear | 16 | – | – |
| amniotic fluid turbidity I° | 1 | – | – |
| amniotic fluid turbidity III° | 2 | – | – |
| Birth weight, kg | 3(2.70-3.33) | 3.1(2.80-3.40) | <0.001 |
| Apgar score | |||
| Apgar 1min | 10(9-10) | 10(10-10) | – |
| Apgar 5min | 10(10-10) | 10(10-10) | – |
| Apgar 10min | 10(10-10) | 10(10-10) | – |
| Postpartum conditions | |||
| breastfeeding | 0 | – | – |
| Fever | 0 | – | – |
&: This is the pregnancy risk grading system implemented in Guangzhou for pregnant women. It grades pregnant women based on their basic conditions. Green indicates a favorable condition with a low pregnancy risk; yellow indicates the presence of certain risk factors and a moderate risk; orange indicates a certain threat to the safety of the mother and baby, with a relatively high risk; pink indicates a significant threat to the safety of the mother and baby, with a high risk; red indicates that continuing the pregnancy may endanger the life of the pregnant woman, with an extremely high risk; and purple indicates that the pregnancy is complicated by infectious diseases.