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. 2025 Apr 15;17(4):2721–2729. doi: 10.62347/SWVQ2652

Table 1.

Associated between clinical factors with severe ROM analyzed by univariate analysis

Variable ROM (n = 115) Severe ROM (n = 60) χ2 P value
No. (%) No. (%)
Sex Male 87 (75.7) 46 (76.7) 0.022 0.881
Female 28 (24.3) 14 (23.3)
Age (year) ≤ 52 63 (54.8) 27 (45) 1.511 0.219
> 52 52 (45.2) 33 (55)
BMI (kg/m2) < 22.8 58 (50.4) 28 (46.7) 0.224 0.636
≥ 22.8 57 (49.6) 32 (53.3)
T category T1-T2 12 (10.4) 7 (11.7) 0.062 0.804
T3-T4 103 (89.6) 53 (88.3)
N category N0-N1 67 (58.3) 38 (63.3) 0.423 0.516
N2-N3 48 (41.7) 22 (36.7)
Clinical stage I-III 60 (52.2) 29 (48.3) 0.233 0.630
IV 55 (47.8) 31 (51.7)
IC Yes 84 (73) 39 (65) 1.221 0.269
No 31 (27) 21 (35)
CCRT Yes 98 (85.2) 48 (80) 0.776 0.378
No 17 (14.8) 12 (20)
Target therapy Yes 89 (77.4) 48 (80) 0.158 0.691
No 26 (22.6) 12 (20)
Immunotherapy Yes 15 (13) 7 (11.7) 0.068 0.794
No 100 (87) 53 (88.3)
Smoking Yes 40 (34.8) 22 (36.7) 0.061 0.805
No 75 (65.2) 38 (63.3)
Drinking Yes 26 (22.6) 16 (26.7) 0.365 0.551
No 89 (77.4) 44 (73.3)

ROM: radiation-induced oral mucositis; BMI: body mass index; IC: induction chemotherapy; CCRT: concurrent chemoradiotherapy.