Table 2.
Univariate and multivariate analyses of factors influencing severe ROM
| Variable | Univariable analyses | Multivariate analyses | |||
|---|---|---|---|---|---|
|
|
|
||||
| OR (95% CI) | P value | OR (95% CI) | P value | ||
| Sex | Male vs. Female | 0.95 (0.45-1.97) | 0.881 | ||
| Age (year) | ≤ 52 vs. > 52 | 1.48 (0.79-2.77) | 0.220 | 1.50 (0.80-2.82) | 0.205 |
| BMI (kg/m2) | < 22.8 vs. ≥ 22.8 | 1.16 (0.62-2.17) | 0.636 | ||
| T category | T1-T2 vs. T3-T4 | 0.88 (0.33-2.37) | 0.804 | ||
| N category | N0-N1 vs. N2-N3 | 0.81 (0.43-1.54) | 0.516 | ||
| Clinical stage | I-III vs. IV | 1.17 (0.62-2.18) | 0.630 | ||
| IC | No vs. Yes | 0.69 (0.35-1.34) | 0.270 | 0.67 (0.34-1.32) | 0.251 |
| CCRT | No vs. Yes | 0.69 (0.31-1.57) | 0.380 | ||
| Target therapy | No vs. Yes | 1.17 (0.54-2.52) | 0.691 | ||
| Immunotherapy | No vs. Yes | 0.88 (0.34-2.29) | 0.794 | ||
| Smoking | No vs. Yes | 1.09 (0.57-2.08) | 0.805 | ||
| Drinking | No vs. Yes | 1.25 (0.61-2.56) | 0.551 | ||
ROM: radiation-induced oral mucositis; BMI: body mass index; IC: induction chemotherapy; CCRT: concurrent chemoradiotherapy.