Table 4.
Univariate Cox regression analysis of risk factors affecting patients’ outcomes
| Factor | β | S.E. | P | HR | 95% CI | |
|---|---|---|---|---|---|---|
|
| ||||||
| Lower | Upper | |||||
| Age | -0.038 | 0.015 | 0.014 | 0.963 | 0.935 | 0.992 |
| BMI | -0.004 | 0.035 | 0.915 | 0.996 | 0.930 | 1.067 |
| Gender | -0.472 | 0.232 | 0.042 | 0.624 | 0.395 | 0.984 |
| Maximum diameter of tumor | 0.249 | 0.042 | 0.000 | 1.283 | 1.182 | 1.392 |
| History of smoking | -0.841 | 0.225 | 0.000 | 0.431 | 0.278 | 0.670 |
| History of alcohol use | -0.409 | 0.229 | 0.074 | 0.664 | 0.424 | 1.041 |
| ECOG PS | -1.204 | 0.214 | 0.000 | 0.300 | 0.197 | 0.456 |
| Cirrhosis | 1.226 | 0.228 | 0.000 | 3.406 | 2.180 | 5.321 |
| AFP | 1.463 | 0.227 | 0.000 | 4.318 | 2.765 | 6.742 |
| Child Pugh | -0.772 | 0.222 | 0.001 | 0.462 | 0.299 | 0.715 |
| ALT | 0.062 | 0.011 | 0.000 | 1.064 | 1.042 | 1.087 |
| AST | 0.052 | 0.009 | 0.000 | 1.054 | 1.036 | 1.072 |
| Alb | -0.084 | 0.017 | 0.000 | 0.919 | 0.890 | 0.950 |
| TBil | 0.129 | 0.024 | 0.000 | 1.137 | 1.086 | 1.191 |
| Treatment | -0.485 | 0.202 | 0.016 | 0.616 | 0.415 | 0.915 |
Note: BMI, Body Mass Index; ECOG PS, Eastern Cooperative Oncology Group performance status; AFP, Alpha-fetoprotein; ALT, Alanine Aminotransferase; AST, Aspartate Aminotransferase; Alb, Albumin; TBil, Total Bilirubin; Child Pugh, Child-Pugh Score; HR, Hazard Ratio; S.E., Standard Error; CI, Confidence Interval.