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[Preprint]. 2025 May 9:rs.3.rs-6370010. [Version 1] doi: 10.21203/rs.3.rs-6370010/v1

Table 6.

Performance comparison of the baseline CP, existing CPs, and our proposed CP (COMPAC) across demographic subgroups in the chart-reviewed cohort, using only encounters within the corresponding age groups for patient identification.

Rule Sensitivity (95%CI) PPV
(95%CI)
F1-Score
(95%CI)
Age group: 2 ~ 5 (N = 173)
dx ≥ 1 0.597 (0.484, 0.72) 0.822 (0.632, 1.0) 0.69 (0.565, 0.8)
*dx ≥ 2 0.621 (0.54, 0.731) 0.944 (0.85, 1.0) 0.748 (0.667, 0.833)
*CAPriCORN 0.608 (0.515, 0.731) 0.896 (0.75, 1.0) 0.723 (0.615, 0.826)
*PheKB 0.542 (0.414, 0.68) 0.724 (0.526, 0.9) 0.618 (0.476, 0.75)
COMPAC 0.632 (0.533, 0.741) 0.926 (0.8, 1.0) 0.75 (0.654, 0.833)
Age group: 6 ~ 12 (N = 132)
dx ≥ 1 0.648 (0.548, 0.76) 0.949 (0.842, 1.0) 0.768 (0.681, 0.851)
*dx ≥ 2 0.635 (0.552, 0.741) 0.98 (0.9, 1.0) 0.769 (0.702, 0.851)
*CAPriCORN 0.637 (0.556, 0.741) 0.981 (0.9, 1.0) 0.771 (0.702, 0.851)
*PheKB 0.6 (0.5, 0.708) 0.864 (0.7, 1.0) 0.707 (0.596, 0.809)
COMPAC 0.64 (0.559, 0.741) 0.985 (0.9, 1.0) 0.775 (0.706, 0.851)
Age group: 13 ~ 18 (N = 90)
dx ≥ 1 0.594 (0.5, 0.704) 0.83 (0.65, 0.951) 0.691 (0.578, 0.792)
*dx ≥ 2 0.636 (0.556, 0.741) 1 (1.0, 1.0) 0.777 (0.714, 0.851)
*CAPriCORN 0.632 (0.545, 0.741) 0.972 (0.9, 1.0) 0.765 (0.691, 0.844)
*PheKB 0.593 (0.5, 0.704) 0.85 (0.7, 1.0) 0.697 (0.596, 0.8)
COMPAC 0.632 (0.556, 0.741) 0.973 (0.9, 1.0) 0.765 (0.692, 0.844)

Note: *Each visit can count only 1 diagnosis (dx) or 1 medication (ICS or BDR) or 1 keyword (kw).