Table 2. Procedural and clinical characteristics of patients stratified by quintiles.
Values are presented as number (percentage).
| Variable | Quintile 1 (Q1) | Quintile 2 (Q2) | Quintile 3 (Q3) | Quintile 4 (Q4) | Quintile 5 (Q5) | P-value (trend) |
|---|---|---|---|---|---|---|
| Total number of patients | 78,670 (100%) | 87,405 (100%) | 87,405 (100%) | 86,069 (100%) | 97,475 (100%) | <0.0001 |
| STEMI | 12,589 (16.0%) | 14,841 (17.0%) | 15,350 (17.6%) | 16,437 (19.1%) | 19,803 (20.3%) | <0.0001 |
| Stable Angina | 24,375 (31.0%) | 27,684 (31.7%) | 28,500 (32.6%) | 29,124 (33.8%) | 31,612 (32.4%) | <0.0001 |
| NSTEMI | 30,177 (38.4%) | 30,937 (35.4%) | 31,054 (35.5%) | 32,714 (38.0%) | 34,036 (34.9%) | 0.08 |
| Q-wave on presenting ECG | 5,100 (6.5%) | 6,875 (7.9%) | 8,000 (9.2%) | 8,035 (9.3%) | 8,988 (9.2%) | 0.12 |
| Arterial access | ||||||
| Femoral | 2,555 (3.2%) | 2,640 (3.0%) | 2,422 (2.8%) | 2,576 (3.0%) | 2,623 (2.7%) | 0.07 |
| Radial | 6,706 (8.5%) | 8,498 (9.7%) | 9,060 (10.4%) | 9,476 (11.0%) | 10,348 (10.6%) | <0.0001 |
| Pre-procedure TIMI flow | ||||||
| 0 | 3,119 (4.0%) | 3,660 (4.2%) | 4,100 (4.7%) | 4,130 (4.8%) | 4,860 (5.0%) | <0.0001 |
| 1 | 752 (1.0%) | 1,044 (1.2%) | 1,331 (1.5%) | 1,410 (1.6%) | 1,625 (1.7%) | <0.0001 |
| 2 | 1,395 (1.8%) | 1,842 (2.1%) | 2,022 (2.3%) | 2,290 (2.7%) | 2,775 (2.9%) | <0.0001 |
| 3 | 3,059 (3.9%) | 3,558 (4.1%) | 3,714 (4.2%) | 3,950 (4.6%) | 4,330 (4.4%) | <0.0001 |
| Cardiogenic shock pre-procedure | 262 (0.3%) | 402 (0.5%) | 496 (0.6%) | 537 (0.6%) | 838 (0.9%) | <0.0001 |
| Vessel attempted | ||||||
| LM | 142 (0.18%) | 202 (0.23%) | 230 (0.26%) | 237 (0.28%) | 241 (0.25%) | 0.11 |
| LAD | 3,479 (4.4%) | 4,190 (4.8%) | 4,640 (5.3%) | 4,970 (5.8%) | 5,580 (5.7%) | 0.48 |
| RCA | 2,416 (3.1%) | 3,400 (3.9%) | 3,460 (4.0%) | 3,780 (4.4%) | 3,970 (4.1%) | 0.23 |
| LCx | 1,925 (2.5%) | 2,850 (3.3%) | 2,915 (3.3%) | 3,065 (3.6%) | 3,760 (3.9%) | 0.06 |
| Grafts | 405 (0.5%) | 655 (0.8%) | 748 (0.9%) | 737 (0.9%) | 763 (0.8%) | 0.14 |
| MVD | 3,519 (4.5%) | 4,275 (4.9%) | 4,615 (5.3%) | 4,935 (5.7%) | 5,900 (6.0%) | 0.03 |
| Anti-thrombotic agent used | ||||||
| Heparin only | 25,051 (31.8%) | 29,784 (34.1%) | 32,495 (37.2%) | 34,940 (40.6%) | 38,530 (39.5%) | <0.0001 |
| Heparin + GPIIb/IIIa | 8,641 (11.0%) | 11,678 (13.4%) | 12,578 (14.4%) | 13,365 (15.5%) | 14,745 (15.1%) | <0.0001 |
| Bivalirudin | 3,107 (3.9%) | 4,285 (4.9%) | 4,448 (5.1%) | 4,570 (5.3%) | 5,485 (5.6%) | 0.14 |
| Warfarin | 1,200 (1.5%) | 1,780 (2.0%) | 2,062 (2.4%) | 2,222 (2.6%) | 2,562 (2.6%) | 0.12 |
| Any circulatory support | ||||||
| IABP used | 2,031 (2.6%) | 2,878 (3.3%) | 3,056 (3.5%) | 3,200 (3.7%) | 3,535 (3.6%) | <0.0001 |
| Ventilated | 1,336 (1.7%) | 1,901 (2.2%) | 2,086 (2.4%) | 2,250 (2.6%) | 2,573 (2.6%) | 0.018 |
| Post-procedure TIMI flow | ||||||
| 0 | 892 (1.1%) | 1,085 (1.2%) | 1,171 (1.3%) | 1,251 (1.5%) | 1,472 (1.5%) | 0.04 |
| 1 | 216 (0.3%) | 293 (0.3%) | 339 (0.4%) | 393 (0.5%) | 468 (0.5%) | 0.03 |
| 2 | 1,020 (1.3%) | 1,233 (1.4%) | 1,317 (1.5%) | 1,391 (1.6%) | 1,536 (1.6%) | <0.0001 |
| 3 | 6,342 (8.1%) | 7,555 (8.6%) | 8,073 (9.2%) | 8,475 (9.8%) | 26,123 (26.8%) | <0.0001 |
Notes.
- ACS
- acute coronary syndrome
- ECG
- electrocardiogram
- IABP
- intra-aortic balloon pump
- LAD
- left anterior descending artery
- LCx
- left circumflex artery
- LM
- left main artery
- MVD
- multivessel disease
- NSTEMI
- non-ST-segment elevation myocardial infarction
- PCI
- percutaneous coronary intervention
- RCA
- right coronary artery
- STEMI
- STsegment-elevation myocardial infarction
- TIMI
- Thrombolysis in Myocardial Infarction
- GPIIb/IIIa
- glycoprotein IIb/IIIa inhibitor