Table 2. Cost-effectiveness of CMV vaccination strategies.
| Vaccination strategy | Cost (million US$) | DALY | ICER (US$/DALY averted) versus status quo | ICER (US$/DALY averted) versus next best |
|---|---|---|---|---|
| No vaccination | 4 26 696 (4 25 979–4 27 414) | 9 346 456 | – | – |
| (9 328 596–9 364 316) | ||||
| pre-marriage vaccination | 435 686 | 7 371 399 | 4751 | 4751 |
| (4 34 777–4 36 596) | (7 356 764–7 386 033) | (4124–5378) | (4124–5378) | |
| Reproductive-age vaccination | 457 021 | 6 549 424 | 10 814 | 25 553 |
| (4 54 882–4 57 470) | (6 536 887–6 561 960) | (10 290–11 338) | (12 566–36 126) |
Costs and DALYs were discounted at 3%. Data are presented as medium and 95% uncertainty interval (Ul).
cCMV, congenital cytomegalovirus; CMV, cytomegalovirus; DALY, disability-adjusted life year; ICER, incremental cost-effectiveness ratio.