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. 2025 May 12;3(1):e002522. doi: 10.1136/bmjph-2024-002522

Table 2. Cost-effectiveness of CMV vaccination strategies.

Vaccination strategy Cost (million US$) DALY ICER (US$/DALY averted) versus status quo ICER (US$/DALY averted) versus next best
No vaccination 4 26 696 (4 25 979–4 27 414) 9 346 456
(9 328 596–9 364 316)
pre-marriage vaccination 435 686 7 371 399 4751 4751
(4 34 777–4 36 596) (7 356 764–7 386 033) (4124–5378) (4124–5378)
Reproductive-age vaccination 457 021 6 549 424 10 814 25 553
(4 54 882–4 57 470) (6 536 887–6 561 960) (10 290–11 338) (12 566–36 126)

Costs and DALYs were discounted at 3%. Data are presented as medium and 95% uncertainty interval (Ul).

cCMV, congenital cytomegalovirus; CMV, cytomegalovirus; DALY, disability-adjusted life year; ICER, incremental cost-effectiveness ratio.