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. 2025 May 15;19:3857–3882. doi: 10.2147/DDDT.S512058

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© 2025 Marei et al.

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Oxidative stress and proinflammatory biomarkers in liver tissue homogenates of fibrosed and treated groups. (A) MDA content (nmol/mL). (B) GSH (mg/g tissue). (C) Liver TNF-α content (pg/mg protein). (D) liver mRNA expression of IL-6 (fold change).

Notes: The data are expressed by bar graph and the values are presented as mean ± SEM; n = 5. * (P ≤ 0.05), ** (P ≤ 0.01), *** (P≤0.001) and **** (P ≤ 0.0001) compared to control group. ## (P ≤ 0.01), ### (P ≤ 0.001) and #### (P ≤ 0.0001) compared to the fibrosis model group. $$ (P ≤ 0.01), compared to the CCl₄ + Clx group.