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. 2025 May 15;19:3857–3882. doi: 10.2147/DDDT.S512058

Table 2.

Hepatic and Renal Biomarkers of the in vivo Toxicity Study Groups

Vehicle Control (CMC) CLX HR1 HR2 HR3
AST (U/L) 150.4 ± 9.53 127.5 ± 14 148.33 ± 4.66 123.33 ± 10.2 142 ± 7.37
ALT (U/L) 32.33 ± 2.73 45.66 ± 0.88 37.33 ± 5.81 35 ± 3 37.66 ± 2.33
ALP (U/L) 125.25 ± 6.56 123 ± 6.59 120.25 ± 18.9 121 ± 11.14 102.2 ± 6.36
Total Bilirubin (mg/dL) 0.05 ± 0.003 0.045 ± 0.006 0.07 ± 0.005 0.065 ± 0.009 0.037 ± 0.004
Albumin (g/dL) 3.72 ± 0.09 3.68 ± 0.04 3.35 ± 0.17 3.61 ± 0.23 3.7 ± 0.08
Creatinine (mg/dL) 0.44 ± 0.056 0.43 ± 0.06 0.39 ± 0.04 0.59 ± 0.06 0.53 ± 0.07

Notes: Values are expressed as a mean ± SEM; (n = 5), No significant difference was recognized between the groups.