Figure 1.
(A)Western blot showing ATM, RAD50, NBS1, MRE11 and H2AX protein levels in HEK293 control and HEK293_PRDX1 KO cells. (B) Western blot showing ATM, RAD50, NBS1, MRE11 and H2AX protein levels in HeLa control and HeLa_PRDX1 KO cells. (C) Clonogenic survival assay showing ATM inhibitor AZ31 sensitivity in HEK293 control and HEK293 PRDX1_KO cells. (D) Clonogenic survival assay showing ATM inhibitor KU55933 sensitivity in HEK293 control and HEK293 PRDX1_KO cells. Survival fraction statistical analysis was performed using a two-way ANOVA test. * p < 0.05, ** p < 0.01.
