Table 1. Joinpoint regression analysis of the incidence rate of hepatitis B in China from 2004 to 2020.

Region	AAPCa (95% CI)		t test	P value
Northern region	0.29 (−1.85 to 2.47)		0.26	.794
Beijing	−9.05 (−15.36 to −2.26)		2.58	.009
Tianjin	−5.08 (−11.02 to 1.27)		−1.58	.114
Hebei	0.98 (−1.38 to 3.39)		0.81	.419
Shanxi	3.21 (−0.41 to 6.97)		1.73	.082
Inner Mongolia	−2.26 (−3.92 to −0.56)		−2.60	.009
Northeast region	−4.09 (−5.60 to −2.56)		−5.17	<.001
Heilongjiang	−5.82 (−8.09 to −3.48)		−4.80	<.001
Jilin	−5.21 (−6.29 to −4.12)		−9.17	<.001
Liaoning	−1.06 (−3.40 to 1.33)		−0.87	.382
Northwest region	−5.64 (−7.48 to −3.75)		−5.75	<.001
Shaanxi	−9.23 (−10.96 to −7.48)		−9.91	<.001
Gansu	−8.31 (−12.63 to −3.77)		−3.52	<.001
Qinghai	−0.45 (−2.73 to 1.88)		−0.38	.701
Ningxia	−9.84 (−11.37 to −8.28)		−12.89	<.001
Xinjiang	0.36 (−3.43 to 4.30)		0.18	.854
Eastern region	0.49 (−0.82 to 1.81)		0.73	.466
Shanghai	3.81 (1.12 to 6.56)		3.04	.008
Jiangsu	−3.61 (−5.11 to −2.06)		4.57	<.001
Zhejiang	−8.43 (−11.25 to −5.52)		5.51	<.001
Fujian	0.18 (−1.0 to 1.41)		0.29	.771
Shandong	3.19 (−0.45 to 6.96)		1.71	.087
Anhui	5.46 (4.35 to 6.59)		9.81	<.001
Jiangxi	0.93 (−0.97 to 2.87)		0.96	.339
Central region	0.84 (−3.79 to 5.69)		0.35	.727
Henan	−3.00 (−8.32 to 2.64)		−1.06	.291
Hubei	-0.38 (−2.69 to 1.98)		−0.32	.750
Hunan	10.52 (7.91 to 13.20)		8.19	<.001
Southern region	4.07 (1.41 to 6.80)		3.02	.002
Guangdong	4.40 (2.01 to 6.83)		3.66	<.001
Hainan	1.38 (−2.62 to 5.55)		0.67	.505
Guangxi	3.22 (0.83 to 5.67)		2.65	.008
Southwest region	3.60 (−4.86 to −2.33)		−5.48	<.001
Chongqing	−9.23 (−11.15 to −7.28)		−8.9	<.001
Sichuan	−4.47 (−6.47 to −2.43)		−4.24	<.001
Guizhou	0.30 (−3.41 to 4.14)		0.15	.877
Yunnan	−2.52 (−5.40 to 0.45)		−1.67	.094
Xizang	16.93 (14.31 to 19.60)		14.73	<.001
Whole country	−0.15 (−1.77 to 1.49)		−0.18	.855

^aAAPC: average annual percentage change.