Table 1.
Baseline Characteristics
| Physical Characteristics | Social Characteristics | ||
| Patients, n | 155 | Marital Status | |
| Age, years (mean ± SD) | 53 ± 13 | Single | 25 (16) |
| Female, n (%) | 126 (81) | Married | 100 (65) |
| Caucasian | 106 (68) | Separated | 4 (3) |
| African-American | 34 (22) | Divorced | 11 (7) |
| Hispanic | 7 (5) | Widowed | 15 (10) |
| Other | 8 (5) | Lives Alone | 21 (14) |
| PAH Diagnosis | Currently employed | 55 (35) | |
| Idiopathic ("Primary") | 63 (41) | Occupation | |
| Familial | 2 (1) | Prof/Exec | 22 (14) |
| Systemic Sclerosis | 32 (21) | Manager | 17 (11) |
| Other CVD | 13 (8) | Clerical | 45 (29) |
| Portal Hypertension | 11 (7) | Skilled Labor | 4 (3) |
| Anorectic Agent Use | 7 (5) | Unskilled Labor | 16 (10) |
| Other (i.e., HIV, PVOD) | 27 (17) | Homemaker | 12 (8) |
| Other | 9 (6) | ||
| WHO I, % | 3 (2) | Not Available | 30 (19) |
| WHO II, % | 80 (52) | Substance Abuse | |
| WHO III, % | 65 (42) | Prior Alcohol | 11 (7) |
| WHO IV, % | 7 (5) | Current Alcohol | 0 (0) |
| Prior Smoking | 66 (43) | ||
| Mean RA pressure (mmHg) | 8.7 ± 2.6 | Current Smoking | 12 (8) |
| Mean PA pressure (mmHg) | 47 ± 17 | ||
| Cardiac output (liters/min) | 4.9 ± 1.8 | ||
| PVR (dynes·sec·cm-5) | 630 ± 425 | Treatments | |
| Symptoms | Epoprostenol | 50 (32) | |
| Dyspnea | 105 (68) | Bosentan | 89 (57) |
| Fatigue, Weakness | 55 (35) | Calcium Channel Blocker | 52 (34) |
| Lightheadedness/Pre-syncope | 31 (20) | Sildenafil | 3 (2) |
| Chest Pain | 31 (20) | Spironolactone | 40 (26) |
| Cough | 27 (17) | Other Diuretic(s) | 76 (49) |
| Leg Pain | 26 (15) | Warfarin | 74 (48) |
| Jaw Pain | 15 (10) | Digoxin | 47 (30) |
| Depression | 15 (10) | Oxygen, continuous | 29 (19) |
| Anxiety | 14 (9) | Oxygen, nocturnal | 17 (11) |
| Palpitations | 15 (10) | Oxygen, as needed | 15 (10) |
| Diarrhea | 22 (14) | ||
| Abdominal Complaints | 7 (6) | ||
| Leg Weakness | 7 (6) | ||
| Difficulty Sleeping | 3 (2) | ||