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. 2025 May 18;24:15347354251339121. doi: 10.1177/15347354251339121

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© The Author(s) 2025

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — Suppressive effects of drugs on CDDP-induced ROS production in PC12 cells. (A) PC12 cells exposed to CDDP for 48 hours with drugs followed by staining cells with H2DCFDA. Values are analyzed by one-way ANOVA and expressed as means ± SD (n = 3). ***P < .001 versus control group; ^#P < .05, ^###P < 0.001 versus CDDP group. (B–D) Western blot analysis of p-p53, p53, γ-H2A.X, and H2A.X in cells treated with TKD (B), TKE (C), or CucD (D). GAPDH was used as a loading control. Full-length blots are presented in Supplemental Figure S2.