Table 2.
Point estimates of beta coefficients and 95% confidence intervals (in square parentheses) from the Bayesian logistic mixed effect model testing for the effects of the three-level categorical fixed effect ‘treatment’ on genotype errors. Included are R2 (the proportion of the total variance explained by the model) and marginal R2 (the proportion of the total variance explained by the fixed effects alone) values.
|
beta coefficient |
[95% CIs] |
|
|---|---|---|
|
fixed effects |
||
|
internal control |
−6.572 |
[−7.658, −4.565] |
|
reused detection plate |
−0.320 |
[−0.739, 0.083] |
|
reused PCR plate |
1.907 |
[1.602, 2.209] |
|
random effects |
||
|
sample ID |
1.302 |
[1.100, 1.533] |
|
DNA plate |
0.388 |
[0.025, 2.864] |
|
multiplexed reaction |
0.348 |
[0.016, 1.571] |
|
locus |
1.273 |
[0.970, 1.759] |
|
number of observations |
30 835 |
|
|
R 2 |
0.117 |
|
|
marginal R2 |
0.001 |